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["Trade Names"," Psychotropic Medications","Last updated and approved+: 10/27/2025"]
["Xanax","ALPRAZOLAM"]
["Xanax XR","ALPRAZOLAM"]
["Elavil","AMITRIPTYLINE HCL"]
["Asendin","AMOXAPINE"]
["Adzenys XR ODT","AMPHETAMINE"]
["Dyanavel XR","AMPHETAMINE"]
["Abilify","ARIPIPRAZOLE"]
["Aristada","ARIPIPRAZOLE LAUROXIL"]
["Nuvigil","ARMODAFINIL"]
["Saphris","ASENAPINE MALEATE"]
["Strattera","ATOMOXETINE HCL"]
["Zulresso","BREXANOLONE"]
["Rexulti","BREXPIPRAZOLE"]
["Aplenzin","BUPROPION HBR"]
["Wellbutrin SR","BUPROPION HCL"]
["Wellbutrin XL","BUPROPION HCL"]
["Forfivo XL","BUPROPION HCL"]
["Zyban","BUPROPION HCL"]
["Buspar","BUSPIRONE HCL"]
["Tegretol","CARBAMAZEPINE"]
["Tegretol XR","CARBAMAZEPINE"]
["Equetro","CARBAMAZEPINE"]
["Epitol","CARBAMAZEPINE"]
["Vraylar","CARIPRAZINE HCL"]
["Librium","CHLORDIAZEPOXIDE HCL"]
["Librax","CHLORDIAZEPOXIDE/CLIDINIUM BR"]
["Thorazine","CHLORPROMAZINE HCL"]
["Largactil","CHLORPROMAZINE HCL"]
["Ormazine","CHLORPROMAZINE HCL"]
["Celexa","CITALOPRAM HYDROBROMIDE"]
["Anafranil","CLOMIPRAMINE HCL"]
["Klonopin","CLONAZEPAM"]
["Catapres","CLONIDINE HCL"]
["Kapvay","CLONIDINE HCL"]
["Tranxene","CLORAZEPATE DIPOTASSIUM"]
["Clozaril","CLOZAPINE"]
["Fazaclo ODT","CLOZAPINE"]
["Versacloz","CLOZAPINE"]
["Norpramin","DESIPRAMINE HCL"]
["Pertofrane","DESIPRAMINE HCL"]
["Pristiq","DESVENLAFAXINE"]
["Focalin","DEXMETHYLPHENIDATE HCL"]
["Focalin XR","DEXMETHYLPHENIDATE HCL"]
["Dexedrine","DEXTROAMPHETAMINE SULFATE"]
["Adderall","DEXTROAMPHETAMINE/AMPHETAMINE"]
["Adderall XR","DEXTROAMPHETAMINE/AMPHETAMINE"]
["Mydayis","DEXTROAMPHETAMINE/AMPHETAMINE"]
["Valium","DIAZEPAM"]
["Benadryl","DIPHENHYDRAMINE"]
["Depakote","DIVALPROEX SODIUM"]
["Depakote ER","DIVALPROEX SODIUM"]
["Depakote Sprinkles","DIVALPROEX SODIUM"]
["Silenor","DOXEPIN HCL"]
["Sinequan","DOXEPIN HCL"]
["Cymbalta","DULOXETINE HCL"]
["Cipralex","ESCITALOPRAM OXALATE"]
["Lexapro","ESCITALOPRAM OXALATE"]
["Prozac","FLUOXETINE HCL"]
["Sarafem","FLUOXETINE HCL"]
["Permitil","FLUPHENAZINE DECANOATE"]
["Prolixin Deconaote (INJ)","FLUPHENAZINE DECANOATE"]
["Prolixin Elixir","FLUPHENAZINE HCL"]
["Modecate","FLUPHENAZINE HCL"]
["Luvox","FLUVOXAMINE MALEATE"]
["Neurontin","GABAPENTIN"]
["Horizant","GABAPENTIN ENACARBIL    "]
["Exxua","GEPIRONE"]
["Intunive ER","GUANFACINE HCL"]
["Guanfacine ER","GUANFACINE HCL"]
["Tenex","GUANFACINE HCL"]
["Haldol","HALOPERIDOL"]
["Haldol Decanoate (AMP)","HALOPERIDOL DECANOATE"]
["Peridol","HALOPERIDOL DECANOATE"]
["Haloperidol LA","HALOPERIDOL DECANOATE"]
["Haldol (AMP)","HALOPERIDOL LACTATE"]
["Atarax","HYDROXYZINE HCL"]
["Vistaril","HYDROXYZINE PAMOATE"]
["Fanapt","ILOPERIDONE"]
["Zomaril","ILOPERIDONE"]
["Tofranil","IMIPRAMINE HCL"]
["Tofranil-PM","IMIPRAMINE PAMOATE"]
["Marplan","ISOCARBOXAZID"]
["Lamictal","LAMOTRIGINE"]
["Dayvigo","LEMBOREXANT"]
["Fetzima","LEVOMILNACIPRAN HCL"]
["Vyvanse","LISDEXAMFETAMINE DIMESYLATE"]
["Eskalith CR","LITHIUM CARBONATE"]
["Lithobid","LITHIUM CARBONATE"]
["Lithium","LITHIUM CITRATE"]
["Ativan","LORAZEPAM"]
["Loxitane","LOXAPINE"]
["Loxitane","LOXAPINE SUCCINATE"]
["Caplyta","LUMATEPERONE TOSYLATE"]
["Latuda","LURASIDONE HCL"]
["Melatonin","MELATONIN"]
["Desoxyn","METHAMPHETAMINE HCL"]
["Methedrine","METHAMPHETAMINE HCL"]
["Ritalin","METHYLPHENIDATE"]
["Ritalin LA","METHYLPHENIDATE"]
["Concerta","METHYLPHENIDATE"]
["Metadate CD","METHYLPHENIDATE"]
["Methylin","METHYLPHENIDATE"]
["Methylin ER","METHYLPHENIDATE"]
["Quillivant XR","METHYLPHENIDATE"]
["Quillichew ER","METHYLPHENIDATE"]
["Aptensio XR","METHYLPHENIDATE"]
["Cotemplat XR-ODT","METHYLPHENIDATE"]
[" Jornay PM","METHYLPHENIDATE"]
["Adhansia XR","METHYLPHENIDATE"]
["Daytrana (PTCH)","METHYLPHENIDATE"]
["Relexxii","METHYLPHENIDATE"]
["Versed","MIDAZOLAM"]
["Remeron","MIRTAZAPINE"]
["Provigil","MODAFINIL"]
["Moban","MOLINDONE HCL"]
["Revia","NALTREXONE"]
["Relistor","NALTREXONE"]
["Serzone","NEFAZODONE HCL"]
["Dutonin","NEFAZODONE HCL"]
["Nefadar","NEFAZODONE HCL"]
["Pamelor","NORTRIPTYLINE HCL"]
["Zyprexa","OLANZAPINE"]
["Symbyax","OLANZAPINE/FLUOXETINE HCL"]
["Lybalvi","OLANZAPINE/SAMIDORPHAN"]
["Serax","OXAZEPAM"]
["Alepam","OXAZEPAM"]
["Trileptal","OXCARBAZEPINE"]
["Oxtellar XR","OXCARBAZEPINE"]
["Invega","PALIPERIDONE"]
["Invega Sustenna","PALIPERIDONE PALMITATE"]
["Invega Trinza (INJ)","PALIPERIDONE PALMITATE"]
["Paxil","PAROXETINE HCL"]
["Paxil CR","PAROXETINE HCL"]
["Brisdelle","PAROXETINE MESYLATE"]
["Pexeva","PAROXETINE MESYLATE"]
["Trilafon","PERPHENAZINE"]
["Etrafon","PERPHENAZINE/AMITRIPTYLINE HCL"]
["Triavil","PERPHENAZINE/AMITRIPTYLINE HCL"]
["Triptafen ","PERPHENAZINE/AMITRIPTYLINE HCL"]
["Nardil","PHENELZINE SULFATE"]
["Nuplazid","PIMAVANSERIN TARTRATE"]
["Orap","PIMOZIDE"]
["Wakix","PITOLISANT"]
["Minipress","PRAZOSIN"]
["Lyrica","PREGABALIN"]
["Inderal","PROPRANOLOL"]
["Inderal LA ","PROPRANOLOL"]
["Vivactil ","PROTRIPTYLINE HCL"]
["Seroquel","QUETIAPINE FUMARATE"]
["Byfavo","REMIMAZOLAM"]
["Risperdal","RISPERIDONE"]
["Risperdal Consta (INJ)","RISPERIDONE MICROSPHERES"]
["Emsam","SELEGILINE"]
["Eldepryl","SELEGILINE"]
["Zelapar","SELEGILINE"]
["Azstarys","SERDEXMETHYLPHENIDATE AND DEXMETHYLPHENIDATE"]
["Zoloft ","SERTRALINE HCL"]
["Alcover","SODIUM OXYBATE"]
["Gamma-OH","SODIUM OXYBATE"]
["Natril","SODIUM OXYBATE"]
["Oxybutyras","SODIUM OXYBATE"]
["Kalceks","SODIUM OXYBATE"]
["Somsanit","SODIUM OXYBATE"]
["Xyrem","SODIUM OXYBATE"]
["Sunosi","SOLRIAMFETOL"]
["Mellaril ","THIORIDAZINE HCL"]
["Navane","THIOTHIXENE"]
["Topamax","TOPIRAMATE"]
["Parnate","TRANYLCYPROMINE SULFATE"]
["Desyrel","TRAZODONE HCL"]
["Desyrel Dividose","TRAZODONE HCL"]
["Oleptro","TRAZODONE HCL"]
["Trazodone D","TRAZODONE HCL"]
["Stelazine","TRIFLUOPERAZINE HCL"]
["Depakene","VALPROIC ACID"]
["Stavzor","VALPROIC ACID"]
["Depacon","VALPROIC ACID"]
["Convulex","VALPROIC ACID (AS SODIUM SALT)"]
["Depakote","VALPROIC ACID (AS SODIUM SALT)"]
["Epilime","VALPROIC ACID (AS SODIUM SALT)"]
["Stavzor","VALPROIC ACID (AS SODIUM SALT)"]
["Valproate","VALPROIC ACID (AS SODIUM SALT)"]
["Effexor","VENLAFAXINE HCL"]
["Viibryd ","VILAZODONE HCL"]
["Qelbree","VILOXAZINE"]
["Trintellix","VORTIOXETINE HYDROBROMIDE"]
["Brintellix","VORTIOXETINE HYDROBROMIDE"]
["Cobenfy","XANOMELINE AND TROSPIUM CHLORIDE"]
["Geodon","ZIPRASIDONE HCL"]
["Geodon","ZIPRASIDONE MESYLATE (Injection)"]
["Zurzuvae","ZURANOLONE"]
[]
[]
[]
[" + Children’s Division has implemented an Excessive Dosage Guide for children in foster care 17 and under. The current recommendations were created by the Psychotropic Medication Advisory Committee (PMAC). Updates will be posted at least annually. "]
["DISCLAIMER: THE CHILDREN'S DIVISION EXCESSIVE DOSAGE GUIDE DOES NOT PROVIDE MEDICAL ADVICE"]
["The information contained herein regarding Excessive Dosage Guide is for informational purposes only and is not intended to be a substitute for professional medical advice, diagnosis or treatment. Always seek the advice of your physician or other qualified health care provider with any questions you may have regarding a medical condition or treatment. The Excessive Dosage Guide will be reviewed and updated by UMKC Drug Information Center and the Psychotropic Medication Advisory Committee – Excessive Dosage Subcommittee.  Official version of the Excessive Dosage Guide is maintained at the "]
["Department of Social Services website."]

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["Trade Names","Generic name","Proposed new Max Dosage\nFDA approval or PMAC recommendation\n\n(IF ANY PSYCHOTROPIC MEDICATION EXCEEDS MAXIMUM DOSAGE, OUTSIDE OF AGE GUIDELINES LISTED BELOW, OR SAFETY AND EFFICACY HAVE NOT BEEN ESTABLISHED  - REFERRAL TO CFE IS REQUIRED PRIOR TO CONSENT)"]
["Xanax, Xanax XR","ALPRAZOLAM","7+ years: 3 mg "]
["Elavil","AMITRIPTYLINE HCL","12+ years: 200 mg"]
["Asendin","AMOXAPINE","Safety and efficacy have not been established"]
["Adzenys XR ODT, Dyanavel XR","AMPHETAMINE","Adzenys XR:\n6-12 years:  18.8 mg/day\n13+ years:  12.5mg/day\n\nDynavel XR: \n6+ years: 20 mg/day"]
["Abilify","ARIPIPRAZOLE","\n6-9 years: dose 15 mg \n10+ years: 30 mg "]
["Aristada","ARIPIPRAZOLE LAUROXIL","Safety and efficacy have not been established"]
["Nuvigil","ARMODAFINIL","Safety and efficacy have not been established"]
["Saphris","ASENAPINE MALEATE","10+ years:  20 mg"]
["Strattera","ATOMOXETINE HCL","6+ years:\nChildren < 70 kg: 1.4 mg/kg/day\nChildren  70 kg +: 100 mg/day"]
["Zulresso","BREXANOLONE","15+ years: 90 mcg/kg/hour continuous infusion"]
["Rexulti","BREXPIPRAZOLE","13-17 years: 4 mg/day"]
["Aplenzin","BUPROPION HBR","Safety and efficacy have not been established"]
["Wellbutrin SR, Wellbutrin XL, Forfivo XL, Zyban","BUPROPION HCL","Immediate Release:\n6+ years:  150 mg/single dose max\n\nExtended Release:\n6+ years:  300 mg/single dose max"]
["Buspar","BUSPIRONE HCL","6+ years: 60 mg/day "]
["Tegretol, Tegretol XR, Equetro, Epitol","CARBAMAZEPINE","0-5 years: 35 mg/kg \n6-14 years: 1,000 mg\n15+: 1,200 mg"]
["Vraylar","CARIPRAZINE HCL","Safety and efficacy have not been established"]
["Librium","CHLORDIAZEPOXIDE HCL"," 6+ years:  30 mg"]
["Librax","CHLORDIAZEPOXIDE/CLIDINIUM BR","Safety and efficacy have not been established"]
["Thorazine, Largactil, Ormazine","CHLORPROMAZINE HCL","5-12 years: 200 mg oral, 40 mg IM\n13+ years: 500 mg oral, 75 mg IM "]
["Celexa","CITALOPRAM HYDROBROMIDE","7+ years:  40 mg"]
["Anafranil","CLOMIPRAMINE HCL","10+ years:  200 mg"]
["Klonopin","CLONAZEPAM","4 mg/day for psychiatric disorders "]
["Catapres, Kapvay","CLONIDINE HCL","Immediate Release\n4-5 years:  0.1mg/day\n\n6+ years:\nUnder 27kg:  0.1mg/day\n27-40.5kg: 0.2 mg/day\n40.6-45kg: 0.3 mg/day\nif 45kg or more: 0.4 mg/day\n\nExtended Release:\n4-5 years:  0.1mg/day\n6+ years: 0.4 mg/day"]
["Tranxene","CLORAZEPATE DIPOTASSIUM","9-12 years: 60 mg/day\n13+ years: 90 mg/day"]
["Clozaril, Fazaclo ODT, Versacloz","CLOZAPINE","6+ years:  400 mg"]
["Norpramin, Pertofrane","DESIPRAMINE HCL","6 -12 years: 100 mg \n13+ years: 150 mg "]
["Pristiq","DESVENLAFAXINE","7-11 years: 50mg\n12+ years: 100mg"]
["Focalin, Focalin XR","DEXMETHYLPHENIDATE HCL","6+ years: \nImmediate Release: 20 mg/day\nExtended Release: 30 mg/day"]
["Dexedrine","DEXTROAMPHETAMINE SULFATE","Immediate Release\n3+ years: 40 mg\n\nExtended Release\n6+ years: 40 mg"]
["Adderall, Adderall XR, Mydayis","DEXTROAMPHETAMINE/AMPHETAMINE","Immediate Release\n3+ years: 40 mg\n\nExtended Release \n6+ years: 30 mg\nif 50kg or more: 60 mg \n\nMydayis\n13-17 years: 25 mg"]
["Valium","DIAZEPAM","Safety and efficacy have not been established"]
["Benadryl","DIPHENHYDRAMINE","Max Dosage:\nOral and IV: 300 mg\n\nCommon Cold:\n6-12 years: max 150mg\n12+ years: 300 mg\n\nInsomnia:\n12+years: 50mg\n\nPruritus: topical only"]
["Depakote, Depakote ER, Depakote Sprinkles","DIVALPROEX SODIUM","Divalproex sodium: \n 5+ years - 1000 mg"]
["Silenor, Sinequan","DOXEPIN HCL","7-11 years:  75 mg\n12+ years:  150mg/day"]
["Cymbalta","DULOXETINE HCL","7+ years:  120 mg"]
["Cipralex, Lexapro","ESCITALOPRAM OXALATE","7+ years:  20 mg"]
["Prozac, Sarafem","FLUOXETINE HCL","6-11 years: 40 mg/day\n12+ years: 60 mg/day\n"]
["Permitil, Prolixin Deconaote (INJ)","FLUPHENAZINE DECANOATE","Safety and efficacy have not been established"]
["Prolixin Elixir, Modecate","FLUPHENAZINE HCL","6+ years: 12mg/day"]
["Luvox","FLUVOXAMINE MALEATE","8 - 11 years: 200 mg;\n12+ years: 300 mg"]
["Neurontin","GABAPENTIN","3-4 years: 40 mg/kg \n5-11 years: 35 mg/kg \n12+ years: 2,400 mg"]
["Horizant","GABAPENTIN ENACARBIL    ","Safety and efficacy of extended-release products have not been established"]
["Exxua","GEPIRONE","Safety and efficacy have not been established"]
["Tenex (IR), Intuniv (ER), Guanfacine ER","GUANFACINE HCL","Immediate Release: \n4-5 years:  1mg\n6+ years\nunder 27 kg:  1mg\n27-40.5kg: 2 mg;\n40.6-45kg: 3 mg;\n45kg or more: 4 mg\n\nExtended Release: \n4-5 years: 1mg/day\nChildren 6 to 12 years: 4 mg/day;\nAdolescents: 13 to 17 years: 7 mg/day."]
["Haldol","HALOPERIDOL","3+ years:  15 mg/day "]
["Haldol Decanoate (AMP), Peridol, Haloperidol LA","HALOPERIDOL DECANOATE","Safety and efficacy have not been established"]
["Haldol (AMP)","HALOPERIDOL LACTATE","3-12 years: 6 mg/day\n13+ years: 15 mg/day"]
["Atarax","HYDROXYZINE HCL","0-5 years: 50 mg\n6+ years: 100 mg"]
["Vistaril","HYDROXYZINE PAMOATE","0-5 years: 50 mg\n6+ years: 100 mg"]
["Fanapt, Zomaril","ILOPERIDONE","Safety and efficacy have not been established"]
["Tofranil","IMIPRAMINE HCL","6-12 years: 50mg\n13+: 75mg"]
["Tofranil-PM","IMIPRAMINE PAMOATE","Safety and efficacy have not been established"]
["Marplan","ISOCARBOXAZID","0-15 years:   safety and efficacy have not been established\n\n16+ years: 60 mg/day"]
["Lamictal","LAMOTRIGINE","Immediate Release\n2-12 years: 400 mg\n13+ years: 500 mg\n\nExtended Release\n13+ years: 600 mg\n*max dose varies based on adjunct medications"]
["Dayvigo","LEMBOREXANT","Safety and efficacy have not been established"]
["Fetzima","LEVOMILNACIPRAN HCL","Safety and efficacy have not been established"]
["Vyvanse","LISDEXAMFETAMINE DIMESYLATE","6+ years:  70 mg"]
["Eskalith CR, Lithobid","LITHIUM CARBONATE","IR:\n7+ years: 1200 mg\nXR:\n12+ years: 1200 mg"]
["Lithium","LITHIUM CITRATE","7+ years: 32 mEq/day in divided doses"]
["Ativan","LORAZEPAM","2 mg single dose max\n6 mg/day total "]
["Loxitane","LOXAPINE","Safety and efficacy have not been established"]
["Loxitane","LOXAPINE SUCCINATE","Safety and efficacy have not been established"]
["Caplyta","LUMATEPERONE TOSYLATE","Safety and efficacy have not been established"]
["Latuda","LURASIDONE HCL","10+ years:  80 mg"]
["Melatonin","MELATONIN","6+ years: 6mg"]
["Desoxyn, Methedrine","METHAMPHETAMINE HCL","6+ years:  25 mg/day"]
["Ritalin, Ritalin LA, Concerta, Metadate CD, Methylin, Methylin ER, Quillivant XR, Quillichew ER, Aptensio XR, Cotemplat XR-ODT, Jornay PM,  Adhansia XR, Daytrana (PTCH), Relexxii","METHYLPHENIDATE","6-12 years: Concerta 54 mg/day\n\n13+ years: Concerta 72 mg/day\n\n6+ years:\nAdhansia XR 85 mg/day\n\nAptensio X: 60 mg/day\n\nCotempla XR ODT 51.8 mg,\n\nDaytrana 30 mg (max dose available, titrate until effect shown)\n\nJornay PM 100 mg/day\n\nMetadate CD 60 mg/day or if 50+kg 100 mg/day\n\nMetadade ER/Ritalin SR 60 mg/day or if 50+kg 100 mg/day\n\nMethylin: 60mg/day\n\nQuillieCHEW ER 60 mg/day\n\nQuillivant XR 60mg/day\n\nRelexxii:\n6 to 12 years: 54 mg\n13+ years:  72 mg\n\nRitalin and Ritalin LA: 60 mg/day or if 50+kg: 100 mg/day"]
["Versed","MIDAZOLAM","0-5 years:10 mg IM\n\n6 months-5 years: 6 mg IV\n\n6+ years: 10 mg IV or IM\n\n1- 5 months: 0.2 mg/kg Intranasal; 6+ months: 10 mg Intransal\n\n6 months-15 years: 20 mg Oral"]
["Remeron","MIRTAZAPINE","30 mg"]
["Provigil","MODAFINIL","13+ years:\nif under 30 kg:  300 mg\nif 30kg or more: 400 mg"]
["Moban","MOLINDONE HCL","12+ years:  225 mg"]
["Revia, Relistor","NALTREXONE","50 mg"]
["Serzone, Dutonin, Nefadar","NEFAZODONE HCL"," \nSafety and efficacy have not been established"]
["Pamelor","NORTRIPTYLINE HCL","6+ years:  100 mg/day"]
["Zyprexa","OLANZAPINE","6+ years:  20 mg/day"]
["Symbyax","OLANZAPINE/FLUOXETINE HCL","10+ years:  12mg olanzapine/50mg fluoxetine"]
["Lybalvi ","OLANZAPINE/SAMIDORPHAN","Safety and efficacy have not been established"]
["Serax, Alepam","OXAZEPAM","12+ years:  120 mg/day in divided doses"]
["Trileptal, Oxtellar XR","OXCARBAZEPINE","IR:\n2-4 years:  60 mg/kg/day\n\n5+ years max dose by weight: \n20-29 kg:  900 mg/day\n29.1-39 kg:  1200 mg/day\n39.1 kg or more:  1800 mg/day\n\nAdjunct ER:\n6-16 years: 1800 mg\n17+ years: 2400 mg"]
["Invega","PALIPERIDONE","12+ years:  12 mg"]
["Invega Sustenna, Invega Trinza (INJ)","PALIPERIDONE PALMITATE","7+ years\nBased on literature review: 234 mg monthly\n\nMonitor closely for side effects"]
["Paxil, Paxil CR","PAROXETINE HCL","7+ years:  60 mg"]
["Brisdelle, Pexeva","PAROXETINE MESYLATE","Safety and efficacy have not been established"]
["Trilafon","PERPHENAZINE","12+ years:  16 mg/day"]
["Etrafon, Triavil, Triptafen ","PERPHENAZINE/AMITRIPTYLINE HCL","< 12 years:\nSafety and efficacy have not been established\n\n12+ years outpatient:\nAmitriptyline max dose:  200 mg/day PO\nPerphenazine max dose: 16 mg/day PO"]
["Nardil","PHENELZINE SULFATE","Safety and efficacy have not been established\n\nSelective mutism:\nUp to 60 mg/day with eventual taper based on 1 case series. \nCaution use due to drug & food interactions"]
["Nuplazid","PIMAVANSERIN TARTRATE","Safety and efficacy have not been established"]
["Orap","PIMOZIDE","12+ years:  0.2 mg/kg/day or 10 mg/day"]
["Wakix","PITOLISANT","\n6+ years\nunder 40 kg: 17.8 mg/day\nif 40 kg or more: 35.6 mg/day"]
["Minipress","PRAZOSIN","7+ years:   4mg"]
["Lyrica","PREGABALIN","\n12+ years:  450 mg/day"]
["Inderal, Inderal LA ","PROPRANOLOL","7+ years: 120mg/day"]
["Vivactil ","PROTRIPTYLINE HCL","Safety and efficacy have not been established"]
["Seroquel","QUETIAPINE FUMARATE","10+ years: 600 mg/day"]
["Byfavo","REMIMAZOLAM","Safety and efficacy have not been established"]
["Risperdal","RISPERIDONE","5 - 10 years: 3 mg \n11+ years: 6 mg "]
["Risperdal Consta (INJ)","RISPERIDONE MICROSPHERES","11+ years:  50 mg q2 weeks"]
["Emsam, Eldepryl, Zelapar","SELEGILINE","12+ years: 12 mg patch daily"]
["Azstarys","SERDEXMETHYLPHENIDATE and DEXMETHYLPHENIDATE","6+ years: 52.3mg serdexmethylphenidate/10.4mg dexmethylphenidate\n"]
["Zoloft ","SERTRALINE HCL","6+ years:  200 mg"]
["Alcover, Gamma-OH, Natril, Oxybutyras, Kalceks, Somsanit, Xyrem","SODIUM OXYBATE","7+ years:\n20-29 kg: 6 g/night, \n30-44 kg: 7.5 g/night,\n≥45 kg: 9 g/night"]
["Sunosi","SOLRIAMFETOL","Safety and efficacy have not been established"]
["Mellaril ","THIORIDAZINE HCL","6+ years:  3 mg/kg/day"]
["Navane","THIOTHIXENE","12+ years:  60 mg/day"]
["Topamax","TOPIRAMATE","2-9 years:  200 mg\n10+ years: 400 mg"]
["Parnate","TRANYLCYPROMINE SULFATE","Safety and efficacy have not been established"]
["Desyrel, Desyrel Dividose, Oleptro, Trazodone D","TRAZODONE HCL","18 months-2 years: 100 mg, \n3-5 years: 150 mg, \n6+ years: 200 mg"]
["Stelazine","TRIFLUOPERAZINE HCL","6-12 years: 15 mg/day, \n13+ years: 40 mg/day"]
["Depakene, Stavzor, Depacon","VALPROIC ACID","5+ years: 1000 mg"]
["Convulex, Depakote, Epilim, Stavzor, Valproate","VALPROIC ACID (AS SODIUM SALT)","5+ years: 1000 mg"]
["Effexor","VENLAFAXINE HCL","6-11 Years:  150 mg\n12+ years:  225mg"]
["Viibryd ","VILAZODONE HCL","7-11 years: 20 mg/day\n12+ years: 30 mg/day"]
["Qelbree","VILOXAZINE","6+ years: 400 mg/day"]
["Trintellix, Brintellix","VORTIOXETINE HYDROBROMIDE","Safety and efficacy have not been established"]
["Cobenfy","XANOMELINE AND TROSPIUM CHLORIDE","Safety and efficacy have not been established"]
["Geodon","ZIPRASIDONE HCL","10+ years:  160 mg"]
["Geodon","ZIPRASIDONE MESYLATE (Injection) ","5+ years:  20 mg"]
["Zurzuvae","ZURANOLONE","Safety and efficacy have not been established"]
[]
[]
[]
[]
[" FDA approved dose or PMAC recommended dose is for/based on non-psychiatric indication "]
["Last updated and approved+:  10/27/2025"]
[" + Children’s Division has implemented an Excessive Dosage Guide for children in foster care 17 and under. The current recommendations were created by the Psychotropic Medication Advisory Committee (PMAC). Updates will be posted at least annually. "]
[]
["DISCLAIMER: THE CHILDREN'S DIVISION EXCESSIVE DOSAGE GUIDE DOES NOT PROVIDE MEDICAL ADVICE"]
["The information contained herein regarding Excessive Dosage Guide is for informational purposes only and is not intended to be a substitute for professional medical advice, diagnosis or treatment. Always seek the advice of your physician or other qualified health care provider with any questions you may have regarding a medical condition or treatment. The Excessive Dosage Guide will be reviewed and updated by UMKC Drug Information Center and the Psychotropic Medication Advisory Committee – Excessive Dosage Subcommittee.  Official version of the Excessive Dosage Guide is maintained "]
["Department of Social Services website."]

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["Trade Names","Generic Name","Proposed new Max Dosage\nFDA approval or PMAC recommendation\n\n(IF ANY PSYCHOTROPIC MEDICATION EXCEEDS MAXIMUM DOSAGE, OUTSIDE OF AGE GUIDELINES LISTED BELOW, OR SAFETY AND EFFICACY HAVE NOT BEEN ESTABLISHED  - REFERRAL TO CFE IS REQUIRED PRIOR TO CONSENT)","FDA Pediatric \nApproved Indication","FDA Adult Approved Dose (per day unless noted)","FDA Pediatric Approved Dose\n(per day unless noted)","Youngest Age With Dosing Recommendations (Not all FDA Approved) ","PMAC Reviewed Dosage for Medications Without FDA Pediatric Approved Dose","Link to Package Insert","Other Resources/information "]
["Xanax, Xanax XR","ALPRAZOLAM","7+ years: 3 mg ","Safety and effectiveness of XANAX in individuals below 18 years of age have not been established.","4mg","7-18 yo: 0.06mg/kg/day","7 yo","> 7 years: 3 mg ",null,"Wolters Kluwer Clinical Drug Information, Inc. (Lexi-Drugs). Wolters Kluwer Clinical Drug Information, Inc.; accessed 7/30/2020"]
["Elavil","AMITRIPTYLINE HCL","12+ years: 200 mg","Depression","300mg","200 mg","12 yo"]
["Asendin","AMOXAPINE","Safety and efficacy have not been established ","Not approved for use in pediatric patients","400mg - outpatient\n600mg - hospitalized","N/A","N/A","Safety and efficacy have not been established"]
["Adzenys XR ODT","AMPHETAMINE","Adzenys XR:\n6-12 years:  18.8 mg/day\n13+ years:  12.5mg/day\n\nDynavel XR: \n6+ years: 20 mg/day","ADHD","12.5mg starting\n18.8 mg max","6.3 mg starting",6,"Adzenys XR:\n6-12 years:  18.8 mg/day\n13+ years:  12.5mg/day\n\nDynavel XR: \n6+ years: 20 mg/day"]
["Abilify","ARIPIPRAZOLE","\n6-9 years: dose 15 mg \n10+ years: 30 mg ","Schizophrenia, Bipolar mania, Irritability associated with autistic disorder, Tourette's disorder","30 mg","Autism - 6-17: 15mg\nBipolar 10-17yo: 30mg",6,"6-10 years: 15 mg\n> 10 years: 30 mg"]
["Aristada","ARIPIPRAZOLE LAUROXIL","Safety and efficacy have not been established","N/A","882 mg per month","N/A","N/A","Safety and efficacy have not been established"]
["Nuvigil","ARMODAFINIL","Safety and efficacy have not been established ","N/A","250 mg","N/A","N/A","< 17 years: \nSafety and efficacy have not been established at this time\n\n> 17 years: \n250 mg/day for narcolepsy and OSA/HS\n150 mg/day for circadian rhythm disruption"]
["Saphris","ASENAPINE MALEATE","10+ years:  20 mg","Bipolar I disorder - Acute monotherapy treatment of manic or mixed episodes, in adults & pedicatric patients 10-17 years of age","20 mg","20 mg","10 yo"]
["Strattera","ATOMOXETINE HCL","6+ years:\nChildren < 70 kg: 1.4 mg/kg/day\nChildren  70 kg +: 100 mg/day","ADHD","100mg","Children < 70 kg: 1.4 mg/kg/day or 100 mg","6 yo"]
["Zulresso","BREXPIPRAZOLE","15+ years: 90 mcg/kg/hour continuous infusion","Schizophrenia","90 mcg/kg/hr","n/a","2 yo","15+ years: 90 mcg/kg/hour continuous infusion",null,"Rosenthal ES, Claassen J, Wainwright MS, et al. Brexanolone as adjunctive therapy in super-refractory status epilepticus. Ann Neurol. 2017;82(3):342-352. doi:10.1002/ana.25008"]
["Rexulti","BREXPIPRAZOLE","13-17 years: 4 mg/day","N/A","4 mg","N/A","N/A","13-17 years: 4 mg/day","https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=2d301358-6291-4ec1-bd87-37b4ad9bd850"]
["Aplenzin","BUPROPION HBR","Safety and efficacy have not been established","N/A","522 mg","N/A","N/A","Safety and efficacy have not been established for extended release tablets or for patients < 6 years\n\n> 6 years:\nIR max dose: 300 mg/day PO for ADHD\nSR max dose: 6 mg/kg/day (300-400 mg/day) PO for depression",null,"Oh DA et al. Single-dose pharmacokinetics of bupropion hydrobromide and metabolites in healthy adolescent and adult subjects. Clin Pharmacol Drug Dev. 2015;4(5):346-53"]
["Wellbutrin SR, Wellbutrin XL, Forfivo XL, Zyban","BUPROPION HCL","Immediate Release:\n6+ years:  150 mg/single dose max\n\nExtended Release:\n6+ years:  300 mg/single dose max","Major Depressive Disorder (MDD) - Safety and effectiveness in the pediatric population have not been established","450 mg \nsmoking cessation: 300mg","6mg/kg (300mg)","6 yo",null,"https://dailymed.nlm.nih.gov/dailymed/fda/fdaDrugXsl.cfm?setid=cbc8c074-f080-4489-a5ae-207b5fadeba3&type=display"]
["Buspar","BUSPIRONE HCL","6+ years: 60 mg/day ","Generalized Anxiety Disorder (GAD)","60 mg","some clinical trials say up to 50mg/day in 5+ yo","5 yo","6+ years: 60 mg/day ","https://dailymed.nlm.nih.gov/dailymed/fda/fdaDrugXsl.cfm?setid=33999f17-f689-40a1-955a-fb19c0590e0e&type=display"]
["Tegretol, Tegretol XR, Equetro, Epitol","CARBAMAZEPINE","0-5 years: 35 mg/kg \n6-14 years: 1,000 mg\n15+: 1,200 mg","Epilepsy, Trigeminal Neuralgi","1600 mg","<6 yo: 35mg/kg \n6-12yo: 1gm\n12-15: 1gm\n15+: 1,200 mg","Non-specific","0-5 years: 35 mg/kg \n6-14 years: 1,000 mg\n15+: 1,200 mg","https://www.accessdata.fda.gov/drugsatfda_docs/label/2009/016608s101,018281s048lbl.pdf"]
["Vraylar","CARIPRAZINE HCL","Safety and efficacy have not been established ","N/A","6 mg","N/A","N/A","Safety and efficacy have not been established at this time\n\n1 study recommended a max dose of 6 mg",null,"Szatmari B et al. Cariprazine Safety in Adolescents and the Elderly: Analyses of Clinical Study Data. Front Psychiatry. 2020"]
["Librium","CHLORDIAZEPOXIDE HCL"," 6+ years:  30 mg","Relief of withdrawal symptoms of acute alcoholism, for parenteral form. ","300 mg/day","30mg","6 yo"]
["Librax","CHLORDIAZEPOXIDE/CLIDINIUM BR","Safety and efficacy have not been established ","N/A","2 caps 4 times per day","N/A","N/A","Safety and efficacy have not been established"]
["Thorazine, Largactil, Ormazine","CHLORPROMAZINE HCL","Children 5-12 years: 200 mg oral, 40 mg IM\n13+ years: 500 mg oral, 75 mg IM ","Schizophrenia, Psychoses, Anxiety and Agitation","800 mg","6+ Years: and adolescents <45.5kg: 50mg (oral)\n<5yo and <22.7kg: IVIM - 40mg\n5+ yo and 22.7-45.5kg: 75mg\n>45.5kg: 800mg","6 MONTHS"]
["Celexa","CITALOPRAM HYDROBROMIDE","7+ years:  40 mg"," Depression; Safety and effectiveness in pediatric patients have not been established. ","40 mg (20mg if <60 yo)","40 mg","7 yo",null,"https://www.accessdata.fda.gov/drugsatfda_docs/label/2019/020822s051lbl.pdf","Dopheide JA. Am J Health Syst Pharm. 2006\nWolters Kluwer Clinical Drug Information, Inc. (Lexi-Drugs). Wolters Kluwer Clinical Drug Information, Inc.; accessed 7/30/2020"]
["Anafranil","CLOMIPRAMINE HCL","10+ years:  200 mg"," OCD; Safety and effectiveness in the pediatric population other than pediatric patients with OCD have not been established. ","250 mg","200 mg","10 yo"]
["Klonopin","CLONAZEPAM","4 mg/day for psychiatric disorders ","N/A","4 mg\n20 mg for seizures\n6 mg for tremors","N/A","N/A","4 mg/day for psychiatric disorders Neuroirritability, agitation (palliative care)\n< 30 kg\nMax daily dose: 0.2 mg/kg/day in 3 doses\n> 30 kg\nMax daily dose: 20 mg/day\n\n\nPanic Disorder 18+ years\nMax dose: 4 mg/day"]
["Catapres, Kapvay","CLONIDINE HCL","Immediate Release\n4-5 years:  0.1mg/day\n\n6+ years:\nUnder 27kg:  0.1mg/day\n27-40.5kg: 0.2 mg/day\n40.6-45kg: 0.3 mg/day\nif 45kg or more: 0.4 mg/day\n\nExtended Release:\n4-5 years:  0.1mg/day\n6+ years: 0.4 mg/day","Safety and effectiveness in pediatric patients have not been established in adequate and well-controlled trials (immediate release product). ","0.6 mg ","N/A","6 yo","Immediate Release\n4-5 years:  0.1mg/day\n\n6+ years:\nUnder 27kg:  0.1mg/day\n27-40.5kg: 0.2 mg/day\n40.5-45kg: 0.3 mg/day\nif 45kg or more: 0.4 mg/day\n\nExtended Release:\n4-5 years:  0.1mg/day\n6+ years: 0.4 mg/day",null,"Wolters Kluwer Clinical Drug Information, Inc. (Lexi-Drugs). Wolters Kluwer Clinical Drug Information, Inc.; accessed 7/30/2020"]
["Tranxene","CLORAZEPATE DIPOTASSIUM","9-12 years: 60 mg/day\n13+ years: 90 mg/day","Because of lack of sufficient clinical experience, tablets are no recommended for use in patients less than 9 years of age. ","90 mg/day","9-12yo: 60mg/day\n>12: 90mg/day","9 yo"]
["Clozaril, Fazaclo ODT, Versacloz","CLOZAPINE","6+ years:  400 mg","Safety and effectiveness in pediatric patients have not been established.  ","900 mg","400 mg","6 yo"]
["Norpramin, Pertofrane","DESIPRAMINE HCL","6 -12 years: 100 mg \n13+ years: 150 mg ","depression/ADHD.   Consideration for drug use in child or adolescent must balance the potential risk with the clinical need (see ADVERSE REACTIONS-Cardiovascular). ","300 mg/day","ADHD: 5+ yo: no max, 7-13yo: 100mg/day\nDepression: 6-12: 5mg/kg/day, adolescents 150mg/day","5 yo","6 -12 years: 100 mg \n> 12 years: 150 mg "]
["Pristiq","DESVENLAFAXINE","7-11 years: 50mg\n12+ years: 100mg","N/A","Up to 400 mg Studied","N/A","N/A","7-11 years: 50mg\n12+ years: 100mg",null,"Findling RL et al. Safety and tolerability of desvenlafaxine in children and adolescents with major depressive disorder. J Child Adolesc Psychopharmacol. 2014;24(4):201–209\nAtkinson Set al. Desvenlafaxine Versus Placebo in the Treatment of Children and Adolescents with Major Depressive Disorder. J Child Adolesc Psychopharmacol. 2018;28(1):55–65"]
["Focalin, Focalin XR","DEXMETHYLPHENIDATE HCL","6+ years: \nImmediate Release: 20 mg/day\nExtended Release: 30 mg/day","CNS stimulant indicated for used to treat ADHD. ","IR: 20mgday\nER: 40mg/day",">6yo: IR 20mg/day ER: 30mg/day","6 yo"]
["Dexedrine","DEXTROAMPHETAMINE SULFATE","Immediate Release\n3+ years: 40 mg\n\nExtended Release\n6+ years: 40 mg","ADHD","60 mg\nIR: not listed","40 mg","3 yo for IR","Immediate Release\n3+ years: 40 mg\n\nExtended Release\n6+ years: 40 mg"]
["Adderall, Adderall XR, Mydayis","DEXTROAMPHETAMINE/AMPHETAMINE","Immediate Release\n3+ years: 40 mg\n\nExtended Release \n6+ years: 30 mg\nif 50kg or more: 60 mg \n\nMydayis\n13-17 years: 25 mg","ADHD","IADHD:\nIR: 40mg; ER: 60mg; triple-bead: 50mg","IR- 3-5yo: 40mg; 6+: 40 mg\nER: 6-12: 30mg (>50kg: 60mg); 13-17: 20mg (>50kg: 60mg)\nMydayis: 25mg\n","3 yo for IR","Immediate Release\n3+ years: 40 mg\n\nExtended Release \n6+ years: 30 mg\nif 50kg or more: 60 mg \n\nMydayis\n13-17 years: 25 mg"]
["Valium","DIAZEPAM","Safety and efficacy have not been established ","Safety and effectiveness in pediatric patients below the age of 6 months have not been established.  ","generally 40-60mg/day","Rectal gel: 20mg/DOSE; IV: 10mg/DOSE (5+yo)","6 MONTHS","Safety and efficacy of extended-release products have not been established"]
["Benadryl","Diphenhydramine","Max Dosage:\nOral and IV: 300 mg\n\nCommon Cold:\n6-12 years: max 150mg\n12+ years: 300 mg\n\nInsomnia, agitation or anxiety:\n12+years: 50mg\n\nPruritus: topical only","allergic conjunctivitis due to foods\nAllergic reaction\nAllergic rhinitis (6+ years)\nAnaphylaxis (w/ epinephrine)\nCommon Cold (6+ years)\nDermatographic urticaria\nInsomnia (12 + years)\nMotion Sickness\nPruritus of skin (2+ years)","400 mg","Max Dosage:\nOral and IV: 300 mg\n\nCommon Cold:\n6-12 years: max 150mg\n12+ years: 300 mg\n\nInsomnia:\n12+years: 50mg\n\nPruritus: topical only","2 yo","Max Dosage:\nOral and IV: 300 mg\n\nCommon Cold:\n6-12 years: max 150mg\n12+ years: 300 mg\n\nInsomnia:\n12+years: 50mg\n\nPruritus: topical only"]
["Depakote, Depakote ER, Depakote Sprinkles","DIVALPROEX SODIUM","Divalproex sodium: \n5+ years - 1000 mg","Pediatric patients under the age of two years are at a considerably increased risk of developing fatal hepatotoxicity, especially those with the aforementioned conditions. ","60 mg/kg/day","Divalproex sodium: 5+ yo - 1000 mg\n","5 yo\nER: 10yo"]
["Silenor, Sinequan","DOXEPIN HCL","7-11 years:  75 mg\n12+ years:  150mg/day","The use of doxepin children under 12 years of age is not recommended because safe conditions for its use have not been established. ","300 mg/day - Insomnia: 6 mg","7 - 11 yo: 3 mg/kg/day,  >12 yo 300mg/day\n150mg/DOSE","7 yo"]
["Cymbalta","DULOXETINE HCL","7+ years:  120 mg","Decreased appetite and weight loss have been observed in association with the use of SSRIs and SNRIs. consequently, regular monitoring of weight and growth should be preformed in children and adolescents treated with SNRIs. ","120 mg","120mg","7 yo"]
["Cipralex, Lexapro","ESCITALOPRAM OXALATE","7+ years:  20 mg","Safety and effectiveness of Lexapro in pediatric patients less than 12 years of age has not been established. ","30mg","20mg","7 yo"]
["Prozac, Sarafem","FLUOXETINE HCL","6-11 years: 40 mg/day\n12+ years: 60 mg/day\n","Safety and effectiveness in pediatric patients have not been established. ","80mg",null,"7 yo","6-11 years: 40 mg/day\n12+ years: 60 mg/day\n"]
["Permitil, Prolixin Deconaote (INJ)","FLUPHENAZINE DECANOATE","Safety and efficacy have not been established ","N/A","100mg","N/A","N/A","Safety and efficacy have not been established\n1 study  used a max dose of 6.25 mg",null,"J Child Adolesc Psychopharmacol. 2017;27(1):2-9\nhttps://pubmed.ncbi.nlm.nih.gov/28112539/"]
["Prolixin Elixir, Modecate","FLUPHENAZINE HCL","6+ years: 12mg/day","N/A","40mg ","N/A",null,"6+ years: 12mg/day"]
["Luvox","FLUVOXAMINE MALEATE","8 - 11 years: 200 mg;\n12+ years: 300 mg","OCD","300mg",null,null,"8 - 11 years: 200 mg;\n12+ years: 300 mg"]
["Neurontin","GABAPENTIN      ","3-4 years: 40 mg/kg \n5-11 years: 35 mg/kg \n12+ years: 2,400 mg","Use of gabapentin as adjunctive therapy in the treatment of partial seizures in pediatric patients 3 to 12 is approved for Pfizer inc.'s gabapentin. However not labeled for pediatric use. ","3.6gm",null,"3 yo","3-4 years: 40 mg/kg \n5-11 years: 35 mg/kg \n12+ years: 2,400 mg"]
["Horizant","GABAPENTIN ENACARBIL    ","Safety and efficacy of extended-release products have not been established"]
["Exxua","GEPIRONE","Safety and efficacy have not been established ","N/A","MDD: Max- 72.6 mg ","N/A","7 years","effect of gepirone was not significantly different from placebo in 2 trials (see label) ","https://www.accessdata.fda.gov/drugsatfda_docs/label/2023/021164s000lbl.pdf"]
["Tenex (IR), Intuniv (ER), Guanfacine ER","GUANFACINE HCL","Immediate Release: \n4-5 years:  1mg\n6+ years\nunder 27 kg:  1mg\n27-40.5kg: 2 mg;\n40.6-45kg: 3 mg;\n45kg or more: 4 mg\n\nExtended Release: \n4-5 years: 1mg/day\nChildren 6 to 12 years: 4 mg/day;\nAdolescents: 13 to 17 years: 7 mg/day.","ADHD; Safety and efficiency of INTUNIV in pediatric patients less than 6 years of age have not been established. ","No max lsited, ADR after 3mg","IR: 6+ yo (27-40.5kg: 2mg; 40.5-45kg: 3mg; >45kg: 4mg)\n\nMonotherapy: Children 6 to 12 years: 4 mg/day; Adolescents: 13 to 17 years: 7 mg/day.\nAdjunct therapy (with psychostimulants): 4 mg/day.","6  yo",null,null,"Wolters Kluwer Clinical Drug Information, Inc. (Lexi-Drugs). Wolters Kluwer Clinical Drug Information, Inc.; accessed 7/30/2020"]
["Haldol","HALOPERIDOL","3+ years:  15 mg/day ","Safety and effectiveness in pediatric patients have not been established. ","100 mg ",null,"3 yo","15 mg"]
["Haldol Decanoate (AMP), Peridol, Haloperidol LA","HALOPERIDOL DECANOATE","Safety and efficacy have not been established ","N/A","450 mg","N/A","N/A","Safety and efficacy have not been established\n\nBased on 1 case report, use of 100 mg every month was safe and effective in an 11 year old boy",null,"https://www.sciencedirect.com/science/article/pii/S0890856709603270?via%3Dihub"]
["Haldol (AMP)","HALOPERIDOL LACTATE","3-12 years: 6 mg/day\n13+ years: 15 mg/day","Safety and effectiveness in pediatric patients have not been established. ","30 mg",null,"3 yo","3-12 years: 6 mg/day\n13+ years: 15 mg/day"]
["Atarax","Hydroxyzine HCL","6+ years: 100 mg\n0-5 years: 50 mg","anxiety, pruritus, sedation","100 mg","6+ years: 100 mg\n0-5 years: 50 mg","2 yo","6+ years: 100 mg\n0-5 years: 50 mg"]
["Vistaril","Hydroxyzine Pamoate","6+ years: 100 mg\n0-5 years: 50 mg","anxiety, pruritus, sedation","100 mg","6+ years: 100 mg\n0-5 years: 50 mg","2 yo","6+ years: 100 mg\n0-5 years: 50 mg"]
["Fanapt, Zomaril","ILOPERIDONE","Safety and efficacy have not been established ","N/A","24 mg","N/A","N/A","Safety and efficacy have not been established\n\nNo recommended max dose at this time"]
["Tofranil","IMIPRAMINE HCL","6-12 years: 50mg\n13+: 75mg","Depression & childhood Enuresis. a dose of 2.5 mg/kg/day of Tofranil should not be exceeded in childhood. ECG charges of unknown significance have been reported in pediatric patients with does twice this amount. ","300 mg","2.5 mg/kg or 100 mg ","8 y o","6-12 years: 50mg\n13+: 75mg"]
["Tofranil-PM","IMIPRAMINE PAMOATE","Safety and efficacy have not been established ","Endogenous depression; Tofranil-PM should not be used in children because of the increased potential for acute overdosage due to the high unit potency. ","300 mg","2.5 mg/kg or 100 mg ","8 y o","Safety and efficacy have not been established"]
["Marplan","ISOCARBOXAZID","0-15 years:   safety and efficacy have not been established\n\n16+ years: 60 mg/day","N/A","60 mg",null,"N/A",">16 years: 60 mg/day\n< 16 years safety and efficacy have not been established"]
["Lamictal","LAMOTRIGINE","Immediate Release\n2-12 years: 400 mg\n13+ years: 500 mg\n\nExtended Release\n13+ years: 600 mg\n*max dose varies based on adjunct medications","Epilepsy; adjunctive therapy in patients age 2 years and older for partial-onset seizures.","600 mg","200 mg","2 yo","Immediate Release\n2-12 years: 400 mg\n13+ years: 500 mg\n\nExtended Release\n13+ years: 600 mg\n*max dose varies based on adjunct medications",null,"Piña-Garza JE, Levisohn P, Gucuyener K, et al. Adjunctive lamotrigine for partial seizures in patients aged 1 to 24 months. Neurology. 2008;70(22 Pt 2):2099-2108. doi:10.1212/01.wnl.0000285493.08622.35"]
["Dayvigo","LEMBOREXANT ","Safety and efficacy have not been established ","n/a","10 mg","n/a","n/a","Safety and efficacy have not been established"]
["Fetzima","LEVOMILNACIPRAN HCL","Safety and efficacy have not been established ","N/A","120 mg",null,"N/A","Safety and efficacy have not been established"]
["Vyvanse","LISDEXAMFETAMINE DIMESYLATE","6+ years:  70 mg","Vyvanse is indicted for use in children aged 6 and older. Under 6 years of age are not recommended. ","70 mg","70 mg","6 yo"]
["Eskalith CR, Lithobid","LITHIUM CARBONATE","IR:\n7+ years: 1200 mg\nXR:\n12+ years: 1200 mg","Treatment for bipolar disorder;  Lithium has not been established in pediatric patients less than 7 years of age with bipolar I disorder.  ","1800 mg","<23 kg: 900 mg, >23 kg: 40 mg/kg/day up to 1500 mg","7 yo, ER 12 yo","IR:\n7+ years: 1200 mg\nXR:\n12+ years: 1200 mg"]
["Lithium","LITHIUM CITRATE","7+ years: 32 mEq/day in divided doses","Treatment of acute manic and mixed episodes in patients 7 years and older; Lithium as not been established in pediatric patients less than 7 years of age with bipolar I disorder. ","48 mEq","not reported, up to 40 mEq","7 yo","7+ years: 32 mEq/day in divided doses",null,"Note to staff:   Dosing based on therapuetic drug levels (lab draws required)"]
["Ativan","LORAZEPAM","2 mg single dose max\n6 mg/day total ","Anxiety","10 mg","2 mg/dose","N/A","2 mg single dose max\n6 mg/day total "]
["Loxitane","LOXAPINE","Safety and efficacy have not been established ","N/A","250 mg","N/A","N/A","Safety and efficacy have not been established\n\nLiterature suggests a max of 15 mg/day PO in adolescent patients off-label for irritability related to autism as add-on therapy (8 – 52 years)"]
["Loxitane","LOXAPINE SUCCINATE","Safety and efficacy have not been established ","N/A","10 mg","N/A","N/A","Clinical safety and efficacy have not been established (no clinical trials at this time).\n\n2 PK studies used 2.5 or 5 mg/day if their body weight was < 50 kg and 5 or 10 mg/day if body weight > 50 kg",null,"Hellings JA et al. Low dose loxapine: neuromotor side effects and tolerability in autism spectrum disorders. J Child Adole Psychopharm. 2015;25:628-624.\n"]
["Caplyta","LUMATEPERONE TOSYLATE","Safety and efficacy have not been established ","n/a","42 mg","n/a","n/a","n/a",null,null," "]
["Latuda","LURASIDONE HCL","10+ years:  80 mg"," Treatmemt of depressive episodes associate with Bipolar I Disorder in patients 10+ years old; Schizophrenia;  Safety and effectiveness in pediatric patients have not been established. ","160 mg","80 mg","10 yo"]
["Melatonin","Melatonin","6+ years: 6mg","n/a; OTC product","common use up to 10mg","n/a",null,"6+ years: 6mg",null,"van Geijlswijk, I. M., Korzilius, H. P., and Smits, M. G. The use of exogenous melatonin in delayed sleep phase disorder: a meta-analysis. Sleep 2010;33(12):1605-1614."]
["Desoxyn, Methedrine","METHAMPHETAMINE HCL","6+ years:  25 mg/day","ADHD","60 mg","25 mg","6 yo","6+ years:  25 mg/day"]
["Ritalin, Ritalin LA, Concerta, Metadate CD, Methylin, Methylin ER, Quillivant XR, Quillichew ER, Aptensio XR, Cotemplat XR-ODT, Jornay PM,  Adhansia XR, Daytrana (PTCH), Relexxii","METHYLPHENIDATE","6-12 years: Concerta 54 mg/day\n\n13+ years: Concerta 72 mg/day\n\n6+ years:\nAdhansia XR 85 mg/day\n\nAptensio X: 60 mg/day\n\nCotempla XR ODT 51.8 mg,\n\nDaytrana 30 mg (max dose available, titrate until effect shown)\n\nJornay PM 100 mg/day\n\nMetadate CD 60 mg/day or if 50+kg 100 mg/day\n\nMetadade ER/Ritalin SR 60 mg/day or if 50+kg 100 mg/day\n\nMethylin: 60mg/day\n\nQuillieCHEW ER 60 mg/day\n\nQuillivant XR 60mg/day\n\nRelexxii:\n6 to 12 years: 54 mg\n13+ years:  72 mg\n\nRitalin and Ritalin LA: 60 mg/day or if 50+kg: 100 mg/day","ADD, Narcolepsy; 6 years and over; Daily dosage above 60mg is not recommended.  ","60 mg, Concerta 72 mg, Jornay PM & Adhansia XR 100 mg","2 mg/kg or 60 mg, Concerta 54 mg (age 6-12), Concerta 72 (adolescent), Contempla XR ODT 51.8 mg, Jornay PM 100 mg, ","3 yo","6-12 years: Concerta 54 mg/day\n\n13+ years: Concerta 72 mg/day\n\n6+ years:\nAdhansia XR 85 mg/day\n\nAptensio X: 60 mg/day\n\nCotempla XR ODT 51.8 mg,\n\nDaytrana 30 mg (max dose available, titrate until effect shown)\n\nJornay PM 100 mg/day\n\nMetadate CD 60 mg/day or if 50+kg 100 mg/day\n\nMetadade ER/Ritalin SR 60 mg/day or if 50+kg 100 mg/day\n\nMethylin: 60mg/day\n\nQuillieCHEW ER 60 mg/day\n\nQuillivant XR 60mg/day\n\nRelexxii:\n6 to 12 years: 54 mg\n13+ years:  72 mg\n\nRitalin and Ritalin LA: 60 mg/day or if 50+kg: 100 mg/day"]
["Versed","MIDAZOLAM","0-5 years:10 mg IM\n\n6 months-5 years: 6 mg IV\n\n6+ years: 10 mg IV or IM\n\n1- 5 months: 0.2 mg/kg Intranasal; 6+ months: 10 mg Intransal\n\n6 months-15 years: 20 mg Oral","This medication is typically used for procedural sedation and NOT for behavioral/psychatric conditions.\n\nThe safety and efficacy of midazolam for sedation/anxiolysis/amnesia following single dose intramuscular administration, intravenously by intermittent injections and continuous infusion have been established in pediatric and neonatal patients. ","0.6 mg/kg","6 mg if < 5 yo, 10 if 6-16 yo","1 month","0-5 years:10 mg IM\n\n6 months-5 years: 6 mg IV\n\n6+ years: 10 mg IV or IM\n\n1- 5 months: 0.2 mg/kg Intranasal; 6+ months: 10 mg Intransal\n\n6 months-15 years: 20 mg Oral"]
["Remeron","MIRTAZAPINE","30 mg","N/A","45 mg","N/A","N/A","30 mg:  Based on literature review, can use up to 45 mg/day in child and adolescents. Younger patients ages < 12 years used lower doses of 15-22 mg/day. Older patients > 12 years used higher doses of 30-45 mg/day\n\nWhen using for MDD, may consider using higher doses of 30-45 mg/day and monitor closely for ADRs\n\nWhen using as adjunctive for other indications (ADHD, social phobia, ASD, chronic cyclic vomiting syndrome) may consider using lower doses of 7.5-15 mg/day and slowly increase.",null,"https://hhs.texas.gov/sites/default/files/documents/doing-business-with-hhs/provider-portal/facilities-regulation/psychiatric/psychiatric-drug-formulary.pdf"]
["Provigil","MODAFINIL","13+ years:\nif under 30 kg:  300 mg\nif 30kg or more: 400 mg","Narcolepsy; Safety and effectiveness in individuals below 16 years of age have not been established. ","400 mg","340 mg if < 30kg, 425 mg if > 30 kg","6 yo","13+ years:\nif under 30 kg:  300 mg\nif 30kg or more: 400 mg"]
["Moban","MOLINDONE HCL","12+ years:  225 mg","Schizophrenia","225 mg","225 mg","12 yo"]
["Revia, Relistor","NALTREXONE","50 mg","n/a","Substance Use Disorder (opioid or alcohol): 50 mg/day ","N/A","Prevention of self harm (ASD) studied in as young as 3 years old / Prevention of substance use/ eating disorders: 15 years old ","Nearly all studies use doses < 50 mg per day with many starting at 25 mg initially ","https://www.accessdata.fda.gov/drugsatfda_docs/label/2013/018932s017lbl.pdf","https://pubmed.ncbi.nlm.nih.gov/16735648/ \n\nhttps://pubmed.ncbi.nlm.nih.gov/31313939/ \n\nhttps://pubmed.ncbi.nlm.nih.gov/23489253/"]
["Serzone, Dutonin, Nefadar","NEFAZODONE HCL","Safety and efficacy have not been established ","N/A","600 mg","N/A","N/A","Children:\n< 7 years: safety and efficacy have not been established\n\n7-11 years: 300 mg/day (limited data available)\n\nAdolescents: \n600 mg/day\n\nLiterature review agrees with above recommendation",null,"Wilens TE et al. Case study: nefazodone for juvenile mood disorders. J Am Acad Child Adolesc Psychiatry. 1997;36(4):481-5\nFindling et al. Nefazodone pharmacokinetics in depressed children and adolescents. J Am Acad Child Adolesc Psychiatry. 2000;39(8):1008-16"]
["Pamelor","NORTRIPTYLINE HCL","6+ years:  100 mg/day","Not approved for use in pediatric patients","150 mg","2 mg/kg or 100 mg ","6 yo","6+ years:  100 mg/day"]
["Zyprexa","OLANZAPINE","6+ years:  20 mg/day"," Bipolar I disorder, \nSchizophrenia,\n Depressive Episodes,\n Agitation","30 mg","20 mg","6 yo","6+ years:  20 mg/day"]
["Symbyax","OLANZAPINE/FLUOXETINE HCL","10+ years:  12mg olanzapine/50mg fluoxetine"," Bipolar I, \nSchizophrenia, \ndepressive Episodes, \nAgitation; \nSafety and effectiveness of Zyprexa and fluoxetine in combination in children <10 years of age have not been established. ","18mg/75mg ","12mg/50mg","10 yo"]
["Lybalvi ","OLANZAPINE/SAMIDORPHAN","Safety and efficacy have not been established ","N/A","20mg/10mg","N/A","N/A","Safety and efficacy have not been established"]
["Serax, Alepam","OXAZEPAM","12+ years:  120 mg","Anxiety;Safety and effectiveness in pediatric patients under 6 years of age have not been established. Absolute dosage of pediatric patients 6 to 12 years of age is not established. ","120 mg","120 mg","12 yo"]
["Trileptal, Oxtellar XR","OXCARBAZEPINE","IR:\n2-4 years:  60 mg/kg/day\n\n5+ years max dose by weight: \n20-29 kg:  900 mg/day\n29.1-39 kg:  1200 mg/day\n39.1 kg or more:  1800 mg/day\n\nAdjunct ER:\n6-16 years: 1800 mg\n17+ years: 2400 mg","Partial seizures in children aged 4 and above with epilepsy; and as adjunctive therapy in children aged 4 years and above with epilepsy. ","2400 mg","60 mg/kg/day age 2-4, For age 4-16 max dose by weight: 900 mg if 20-29 kg, 1200 mg if 29.1-39 kg, and 1800 mg if > 39 kg","2 yo","IR:\n2-4 years:  60 mg/kg/day\n\n5+ years max dose by weight: \n20-29 kg:  900 mg/day\n29.1-39 kg:  1200 mg/day\n39.1 kg or more:  1800 mg/day\n\nAdjunct ER:\n6-16 years: 1800 mg\n17+ years: 2400 mg"]
["Invega","PALIPERIDONE","12+ years:  12 mg","Schizophrenia; Safety and effectiveness in patients <18 years of age have not been established. ","12 mg","12 mg","12 yo"]
["Invega Sustenna, Invega Trinza (INJ)","PALIPERIDONE PALMITATE","7+ years\nBased on literature review: 234 mg monthly\n\nMonitor closely for side effects","N/A","234 mg monthly","N/A","N/A","> 7 years\nBased on literature review: 234 mg monthly\n\nMonitor closely for side effects"]
["Paxil, Paxil CR","PAROXETINE HCL","7+ years:  60 mg","SSRI; Safety and effectiveness in the pediatric population have not been established.  ","60 mg IR, 75 mg ER","60 mg ","7 yo"]
["Brisdelle, Pexeva","PAROXETINE MESYLATE","Safety and efficacy have not been established ","SSRI; Safety and effectiveness in the pediatric population have not been established. ","60 mg","60 mg","7 yo"]
["Trilafon","PERPHENAZINE","12+ years:  16 mg/day","Management of the manifestations of psychotic disorders; control of N/V in adults. ","64 mg","32 mg","12 yo","12+ years:  16 mg/day"]
["Etrafon, Triavil, Triptafen ","PERPHENAZINE/AMITRIPTYLINE HCL","< 12 years:\nSafety and efficacy have not been established\n\n12+ years outpatient:\nAmitriptyline max dose:  200 mg/day PO\nPerphenazine max dose: 16 mg/day PO","N/A","200mg/16mg","N/A","N/A","< 12 years:\nSafety and efficacy have not been established\n\n12+ years outpatient:\nAmitriptyline max dose:  200 mg/day PO\nPerphenazine max dose: 16 mg/day PO"]
["Nardil","PHENELZINE SULFATE","Safety and efficacy have not been established\n\nSelective mutism:\nUp to 60 mg/day with eventual taper based on 1 case series. \nCaution use due to drug & food interactions","N/A","90 mg","N/A","N/A","Safety and efficacy have not been established\n\nSelective mutism:\nUp to 60 mg/day with eventual taper based on 1 case series. \nCaution use due to drug & food interactions",null,"https://pubmed.ncbi.nlm.nih.gov/26560144/"]
["Nuplazid","PIMAVANSERIN TARTRATE","Safety and efficacy have not been established ","N/A","34 mg","N/A","N/A","Safety and efficacy have not been established"]
["Orap","PIMOZIDE","12+ years:  0.2 mg/kg/day or 10 mg/day","Used for suppression of motor and phonic tics in patients with Tourette's disorder. Use and efficacy of ORAP in patients less than 12 years of age is limited.  ","10 mg","0.2 mg/kg or 10 mg ","12 yo","12+ years:  0.2 mg/kg/day or 10 mg/day"]
["Wakix","Pitolisant","\n6+ years\nunder 40 kg: 17.8 mg/day\nif 40 kg or more: 35.6 mg/day","Treatment of excessive daytime sleepiness (EDS) in pediatric patients 6 years of age and older with narcolepsy","35.6 mg","under 40 kg: 17.8 mg\nif 40 kg or more: 35.6 mg","2 yo","\n6+ years\nunder 40 kg: 17.8 mg/day\nif 40 kg or more: 35.6 mg/day",null,"ullen LC, Picone M, Tan L, Johnston C, Stark H. 0771 Pitolisant Is A Safe And Effective Treatment For Children With Prader-willi Syndrome (pws). Sleep. 2019;42(Supplement_1):A309-A310. doi:10.1093/sleep/zsz067.769"]
["Minipress","PRAZOSIN","7+ years:   4mg","n/a","Off-Label: PTSD related nightmares: 3-15 mg/day at bedtime ","n/a",">6 months for Scorpion envenomation, PTSD age 7+ (limited number) ","Off-label use in PTSD range of doses 1-4 mg/day ","https://www.accessdata.fda.gov/drugsatfda_docs/label/2009/017442s033lbl.pdf","https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7388897/                             \n\nhttps://journals.lww.com/psychopharmacology/fulltext/2017/02000/prazosin_in_children_and_adolescents_with.17.aspx"]
["Lyrica","PREGABALIN","\n12+ years:  450 mg/day","DPN, PHN, adjunctive therapy for the treatment of partial-onset seizures in patients 1 month of age and older, Fibromyalgia, Neuropathic pain associated with spinal cord injury. ","600 mg","<30 kg: 14 mg/kg/day, \nif >30 kg: 10 mg/kg/day or 600 mg","4 yo","\n12+ years:  450 mg/day"]
["Inderal, Inderal LA ","PROPRANOLOL","7+ years: 120mg/day","n/a","Off-Label: antipsychic-induced akathisia: 120 mg/day // performance anxiety disorder: 60 mg/day ","n/a","7 years for migraine, 8 years old in akathisia, 10 - 12 years for anxiety or aggression in ASD ","Many off-label uses with dose ranges from 20 mg - 600 mg/day in pediatrics.  Most psychiatric indications recommend doses </= 120 mg/day for children without ASD ","https://www.accessdata.fda.gov/drugsatfda_docs/label/2011/016418s080,016762s017,017683s008lbl.pdf","https://pubmed.ncbi.nlm.nih.gov/39174017/\n\nhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC10921255/"]
["Vivactil ","PROTRIPTYLINE HCL","Safety and Efficacy have not been established","Mental depression; Safety and effectiveness in the pediatric population have not been established. ","60 mg",null,null,"Safety and efficacy have not been established","https://www.accessdata.fda.gov/spl/data/e68d74c7-1d6a-4453-bb46-0047047b7527/e68d74c7-1d6a-4453-bb46-0047047b7527.xml#i4i_pediatric_use_id_3b543367-01b6-4306-99c1-074b2dba26ee"]
["Seroquel","QUETIAPINE FUMARATE","10+ years: 600 mg/day","Schizophrenia, Bipolar I disorder Manic episodes, Bipolar disorder depressive episodes","800 mg","800 mg","10 yo","10+ years: 600 mg/day"]
["Byfavo","Remimazolam","Safety and efficacy have not been established ","n/a","5 mg","n/a","n/a","Safety and efficacy have not been established"]
["Risperdal","RISPERIDONE","5 - 10 years: 3 mg \n11+ years: 6 mg ","Antipsychotic indicated for schizophrenia, Irritability associated with autistic disorder, Bipolar I disorder ","8 mg","6 mg","5 yo","5 - 10 years: 3 mg \n> 10 years: 6 mg "]
["Risperdal Consta (INJ)","RISPERIDONE MICROSPHERES","11+ years:  50 mg q2 weeks","N/A","50 mg every 2 weeks","N/A","N/A","\n> 11 years: \nMax used in Indiana study: 12-37.5 mg Q2 weeks\n\nUsed caution < 11 years as there is not a lot of literature in this patient population. In the Indiana study, they used 12.5 – 25 mg Q2 weeks\n\n> 17 years: \nMax used in Indiana study: 50 mg Q 2 weeks",null,"J Child Adolesc Psychopharmacol. 2017;27(1):2-9\nhttps://pubmed.ncbi.nlm.nih.gov/28112539/"]
["Emsam, Eldepryl, Zelapar","SELEGILINE","12+ years: 12 mg patch daily","N/A","12 mg patch","N/A","17 yo","\n< 12 years: patch is contraindicated. Safety and efficacy have not been established at this time.\n> 12 years: 12 mg patch daily",null,"DelBello MP et al. A Double-Blind, Placebo-Controlled Study of Selegiline Transdermal System in Depressed Adolescents. J Child Adolesc Psychopharmacol. 2014;24(6): 311–317"]
["Azstarys","serdexmethylphenidate and dexmethylphenidate","6+ years: 52.3mg serdexmethylphenidate/10.4mg dexmethylphenidate","Attention Deficit Hyperactivity Disorder (ADHD)","N/A","6+ years: 52.3mg serdexmethylphenidate/10.4mg dexmethylphenidate\n","7 yo","52.3mg serdexmethylphenidate/10.4mg dexmethylphenidate\n"]
["Zoloft ","SERTRALINE HCL","6+ years:  200 mg","SSRI used to treat MDD, OCD, PD, PTSD, SAD, PMDD; Established in treatment of OCD in pediatric patients aged 6-17. ","200 mg","OCD: 200 mg","6 yo","Depression and Anxiety Disorders: 200 mg"]
["Alcover, Gamma-OH, Natril, Oxybutyras, Kalceks, Somsanit, Xyrem","SODIUM OXYBATE","7+ years:\n20-29 kg: 6 g/night, \n30-44 kg: 7.5 g/night,\n≥45 kg: 9 g/night","Pediatric patients under the age of 18 years have not been studied.  ","9 g","20-30 kg: 6 g/night, \n30-45 kg: 7.5 g/night, \n>45 kg: 9 g/night","7 yo","7+ years:\n20-29 kg: 6 g/night, \n30-44 kg: 7.5 g/night,\n≥45 kg: 9 g/night"]
["Sunosi","SOLRIAMFETOL ","Safety and efficacy have not been established ","n/a","150 mg","n/a","n/a","Safety and efficacy have not been established"]
["Mellaril ","THIORIDAZINE HCL","6+ years:  3 mg/kg/day","Depression, Anxiety, Agitation, tension, sleep disturbance; Not intended for children under 2 ","800 mg","3 mg/kg/day","6 yo"]
["Navane","THIOTHIXENE","12+ years:  60 mg/day","Schizophrenia; children age 12 and older. ","60 mg","60 mg/day","12 yo","12+ years:  60 mg/day"]
["Topamax","TOPIRAMATE","2-9 years:  200 mg\n10+ years: 400 mg","Epilepsy or seizures associated with Lennox-Gastaut syndrome in patients 2 years of age and older. ","400 mg","9 mg/kg/day","Infants","Seizure dosing \n\n2-9 years:\n< 11 kg:  250 mg\n12-22 kg: 300 mg\n23-31 kg: 350 mg\n32-38 kg: 350 mg\n\n> 38 kg  or 10+ years: 400 mg"]
["Parnate","TRANYLCYPROMINE SULFATE","Safety and efficacy have not been established ","N/A","60 mg","N/A","N/A","Per package insert:\n> 16 years:  60 mg/day PO\n< 16 years: safety and efficacy have not been established"]
["Desyrel, Desyrel Dividose, Oleptro, Trazodone D","TRAZODONE HCL","18 months-2 years: 100 mg, \n3-5 years: 150 mg, \n6+ years: 200 mg","MDD; Safety and effectiveness in the pediatric population have not been established.  ","600 mg","< 3yo: 100 mg, 3-5 yo: 150 mg, > 5 yo: 200 mg","18 months","18 months-2 years: 100 mg, \n3-5 years: 150 mg, \n6+ years: 200 mg"]
["Stelazine","TRIFLUOPERAZINE HCL","6-12 years: 15 mg/day, \n13+ years: 40 mg/day","Schizophrenia; Dosage should be adjusted to the weight of the child and severity of the symptoms.  The dosage are for children, ages 6-12, who are hospitalized or under close supervision. ","50 mg","6-12 yo: 15 mg/day, \n> 12 yo: 40 mg/day","6 yo","6-12 years: 15 mg/day, \n13+ years: 40 mg/day"]
["Depakene, Stavzor, Depacon","VALPROIC ACID","5+ years: 1000 mg","Treatment of simple and complex absence seizures, and adjectively in patients with multiple seizure types which include absence seizures ages 2 and up. ","60 mg/kg/day",">5 yo: 1000 mg","5 yo"]
["Convulex, Depakote, Epilim, Stavzor, Valproate","VALPROIC ACID (AS SODIUM SALT)","5+ years: 1000 mg","Treatment of simple and complex absence seizures, and adjectively in patients with multiple seizure types which include absence seizures ages 2 and up. ","60 mg/kg/day",">5 yo: 1000 mg","5 yo"]
["Effexor","VENLAFAXINE HCL","6-11 Years:  150 mg\n12+ years:  225mg","MDD;  Safety and effectiveness in the pediatric population have not been established. ","XR: 225 mg, IR: 375 mg","150 mg","7 yo","6-11 Years:  150 mg\n12+ years:  225mg"]
["Viibryd ","VILAZODONE HCL","7-11 years: 20 mg/day\n12+ years: 30 mg/day","N/A","40 mg","N/A","N/A","7-11 years: 20 mg/day\n12+ years: 30 mg/day",null,"Durgam S et al. A Phase 3, Double-Blind, Randomized, Placebo-Controlled Study of Vilazodone in Adolescents with Major Depressive Disorder. Paediatr Drugs. 2018; 20(4): 353–363"]
["Qelbree","VILOXAZINE","6+ years: 400 mg/day","Attention Deficit Hyperactivity Disorder (ADHD)","N/A","6+ years: 400 mg","6 yo","6+ years: 400 mg/day"]
["Trintellix, Brintellix","VORTIOXETINE HYDROBROMIDE","Safety and efficacy have not been established ","N/A","20 mg","N/A","N/A","Safety and efficacy have not been established\nBased on literature review:\n\n> 7 years: limited data using up to 20 mg/day.  Current literature gives no supportive recommendation but gives recommended doses for future studies\n\n< 7 years: avoid use (no data)",null,"Findling RL et al. Pharmacokinetics and Safety of Vortioxetine in Pediatric Patients. J Child Adolesc Psychopharmacol. 2017 Aug 1; 27(6): 526–534\nFindling RL et al. A 6-Month Open-Label Extension Study of Vortioxetine in Pediatric Patients with Depressive or Anxiety Disorders. J Child Adolesc Psychopharmacol. 2018 Feb 1; 28(1): 47–54"]
["Cobenfy","XANOMELINE AND TROSPIUM CHLORIDE","Safety and efficacy have not been established","N/A","125 mg xanomeline/ 30 mg trospium twice daily","N/A","N/A","Safety and efficacy have not been established"]
["Geodon","ZIPRASIDONE HCL","10+ years:  160 mg","The safety and effectiveness of Ziprasidone in pediatric patients have not been established.  ","160 mg","<45 kg: 80 mg, >45 kg: 160 mg","5 yo"]
["Geodon","ZIPRASIDONE MESYLATE (Injection) ","5+ years:  20 mg","The safety and effectiveness of Ziprasidone in pediatric patients have not been established.  ","40 mg","20 mg","5 yo"]
["Zurzuvae","ZURANOLONE","Safety and efficacy have not been established ","N/A","Postpartum depression: 50 mg once daily in the evening, up to 14 days ","N/A","N/A",null,"https://www.accessdata.fda.gov/drugsatfda_docs/label/2023/217369s000lbl.pdf"]
[]
[]
[]
[" FDA approved dose or PMAC recommended dose is for/based on non-psychiatric indication "]
["Last updated and approved+:  10/27/2025"]
[" + Children’s Division has implemented an Excessive Dosage Guide for children in foster care 17 and under. The current recommendations were created by the Psychotropic Medication Advisory Committee (PMAC). Updates will be posted at least annually. "]
[]
["DISCLAIMER: THE CHILDREN'S DIVISION EXCESSIVE DOSAGE GUIDE DOES NOT PROVIDE MEDICAL ADVICE"]
["The information contained herein regarding Excessive Dosage Guide is for informational purposes only and is not intended to be a substitute for professional medical advice, diagnosis or treatment. Always seek the advice of your physician or other qualified health care provider with any questions you may have regarding a medical condition or treatment. The Excessive Dosage Guide will be reviewed and updated by UMKC Drug Information Center and the Psychotropic Medication Advisory Committee – Excessive Dosage Subcommittee.  Official version of the Excessive Dosage Guide is maintained at the "]
["Department of Social Services website."]

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["The literature reviewed by the PMAC cited below:"]
[]
[]
[]
[]
[]
[]
["Last updated and approved+:  10/27/2025"]
[" + Children’s Division has implemented an Excessive Dosage Guide for children in foster care 17 and under. The current recommendations were created by the Psychotropic Medication Advisory Committee (PMAC). Updates will be posted at least annually. "]
[]
["DISCLAIMER: THE CHILDREN'S DIVISION EXCESSIVE DOSAGE GUIDE DOES NOT PROVIDE MEDICAL ADVICE"]
["The information contained herein regarding Excessive Dosage Guide is for informational purposes only and is not intended to be a substitute for professional medical advice, diagnosis or treatment. Always seek the advice of your physician or other qualified health care provider with any questions you may have regarding a medical condition or treatment. The Excessive Dosage Guide will be reviewed and updated by UMKC Drug Information Center and the Psychotropic Medication Advisory Committee – Excessive Dosage Subcommittee.  Official version of the Excessive Dosage Guide is maintained at the "]
["Department of Social Services website."]

{"sheet":"DEFINITIONS","index":4,"n_rows":62,"n_cols":5,"rows_kept":62,"cut":false,"hidden":false,"merged":[[2,3,2,4],[12,3,16,4],[19,3,19,8],[20,3,24,9]]}
["Abbreviations/Symbols","\nDefinition"]
["ADR","adverse drug reaction"]
["<","less than",null,"HOW TO CALCULATE WEIGHT BASED DRUGS"]
[">","greater than"]
["≤","less than or equal to",null,"To use the attached hyperlinks, ","kg to lb conversion link"]
["≥","greater than or equal to",null,"please single click on the link "]
["A.M.","morning",null,"to be directed to the website","lb to kg conversion link"]
["ac","before meals"]
["achs","before meals and at bedtime",null,null,"Dosage Calculator mg/kg"]
["AD","right ear"]
["ADHD","attention deficit hyperactivity disorder"]
["Adolescent","age 13 - 17",null,"Last updated and approved+: 10/27/2025"]
["AS","Left ear",null," + Children’s Division has implemented an Excessive Dosage Guide for children in foster care 17 and under. The current recommendations were created by the Psychotropic Medication Advisory Committee (PMAC). Updates will be posted at least annually. "]
["ASD","autism spectrum disorder"]
["AU","both ears"]
["BID","twice a day"]
["D/C, dc, disc","Discontinue"]
["DOSE","amount of drug taken at a particular time"]
["EC","Enteric-coated"]
["gm","gram",null,"DISCLAIMER: THE CHILDREN'S DIVISION EXCESSIVE DOSAGE GUIDE DOES NOT PROVIDE MEDICAL ADVICE"]
["gtt, gtts","drop, drops",null,"The information contained herein regarding Excessive Dosage Guide is for informational purposes only and is not intended to be a substitute for professional medical advice, diagnosis or treatment. Always seek the advice of your physician or other qualified health care provider with any questions you may have regarding a medical condition or treatment. The Excessive Dosage Guide will be reviewed and updated by UMKC Drug Information Center and the Psychotropic Medication Advisory Committee – Excessive Dosage Subcommittee.  Official version of the Excessive Dosage Guide is maintained at the "]
["HS ","at bed time"]
["hx","history"]
["ID","Intradermal"]
["INJ","injection"]
["IR","Immediate release",null,"Department of Social Services website."]
["IV/IM","intravenous/intramuscular"]
["kg","kilogram"]
["mcg","microgram"]
["MDD","major depressive disorder"]
["mEq","milliequivalent"]
["mg","milligram"]
["NPO","nothing by mouth"]
["OCD","obsessive -compulsive disorder"]
["OD, o.d., ","right eye"]
["OM","otitis media"]
["OS, o.s.","left eye"]
["OSA/HS","Obstructive Sleep Apnea Hypopnea Syndrome"]
["OTC","other the counter"]
["OU, o.u.","both eyes"]
["PD","personality disorder"]
["PE","Phenytoin sodium equivalents"]
["PMDD","premenstrual dysphoric disorder"]
["PO","By mouth"]
["PRN","as needed"]
["PTSD","post traumatic stress disorder"]
["q","every"]
["Q2","every 2 "]
["qd","every day"]
["QID","four times a day"]
["QOD","every other day"]
["RCT","Randomized controlled trial"]
["SAD","seasonal affective disorder"]
["selective mutism","complex childhood anxiety disorder "]
["SR","sustained release"]
["SSRI","selective serotonin reuptake inhibitor"]
["stat","immediately"]
["TID","three times a day"]
["u","unit"]
["XR, XL, XT","extended release"]
["YO","years old"]
["yr","year"]