MO HealthNet is continuing the state specific Preferred Drug List and Clinical Edit processes. The following is a listing of therapeutic classes that have been implemented. Please see the implementation schedule for proposed implementation dates for additional classes.

Issue Date Pharmacy Clinical Edit and PDL Description
02/08/16 15 Day Limitation Clinical Edit
11/06/18 15-Day Supply - Oral Oncology
07/12/18 2nd Generation Antihistamine – Decongestant (Low Sedating) Combinations PDL
07/12/18 2nd Generation Antihistamines PDL
04/04/19 5-HTI Serotonin Receptor Agonists (Triptans) PDL
01/10/19 ACE Inhibitors PDL
01/10/19 ACE Inhibitors/Calcium Channel Blocker Combinations PDL
01/10/19 Ace Inhibitors/Diuretic Combinations PDL
07/12/18 Actinic Keratosis Agents – Topical PDL
02/01/19 ADHD Therapy
04/04/19 Alzheimer’s Agents & Cholinesterase Inhibitors PDL 
07/07/11 Ampyra
10/04/18 Amylin Analogs PDL
07/12/18 Androgenic Agents – Topical PDL
01/10/19 Angiotensin Receptor Blocker Diuretic Combinations PDL
01/10/19 Angiotensin Receptor Blockers PDL
01/10/19 Angiotensin II Receptor-Calcium Channel Blocker Combinations PDL
07/12/18 Antibiotic Agents – Inhaled PDL
01/10/19 Anticoagulants Agents: Oral and Subcutaneous PDL
10/04/18 AntiDiabetic Combinations: Oral and Injectable PDL
04/04/19 Antiemetics –5-HT3 Agents & Other PDL
04/04/19 Antiemetics –THC Derivative Agents PDL
07/12/18 Antifungal Agents – Topical PDL
07/12/18 Antifungal (Onychomycosis – Candidiasis) Agents PDL
07/12/18 Antihistamines and Allergy Agents – Ophthalmic PDL
07/12/18 Antihistamines – Intranasal PDL
10/04/18 Antihyperuricemic Agents PDL
04/04/19 Anti-Parkinsonism MAOB Inhibitors PDL
01/10/19 Antiplatelet Agents
04/04/19 Antipsychotics– 2nd Generation (Atypicals) PDL
07/12/18 Antiparasitic Agents – Topical PDL
07/12/18 Atopic Dermatitis Agents (Immunomodulators)
12/14/18 Benzoyl Peroxide-Antibiotic Combination PDL
07/12/18 Beta Adrenergic Agents Long Acting PDL
07/12/18 Beta Adrenergic Agents/Nebulized PDL
07/12/18 Beta Adrenergic Beta Blockers - Short Acting PDL
01/10/19 Beta Adrenergic Blockers and Diuretic Combinations PDL
10/31/17 BiDil® Tablets Clinical Edit
10/04/18 Bile Salts Agents PDL
10/04/18 Bone Deossification Suppression Agents PDL
04/18/19 Bone Ossification Suppression Agents
09/01/17 Botulinum Toxin Clinical Edit
02/01/19 BPH Agents PDL (formerly Androgen Hormone Inhibitors)
04/18/19 Brand Over Generic
01/10/19 Calcium Channel Blockers (Dihydropyridines) PDL
01/10/19 Calcium Channel Blockers (Non-Dihydropyridines) PDL
06/21/18 CAR T Clinical Edit
10/04/18 Cephalosporin Antibiotics – Oral PDL
10/26/18 COPD Anticholinergic Agents PDL
12/03/18 Corlanor Clinical Edit
05/02/19 Corticosteroids and Rhinitis Agents – Intranasal PDL
01/10/19 Corticosteroids Oral – Inhaled PDL
07/12/18 Corticosteroids-Topical PDL
07/12/18 Cough and Cold PDL
04/04/19 COX-2 Inhibitors PDL
10/04/18 Cryopyrin-Associated Periodic Syndrome (CAPS) Agents PDL
04/11/19 Crysvita Clinical Edit
02/28/19 Diabetic Supply Quantity Limit Fiscal Edit
01/10/19 Direct Renin Inhibitors and Combinations PDL
11/13/03 Dolgic LQ® (Acetaminophen/Butalbital/Caffeine)
05/09/19 Dose Optimization Fiscal Edit
10/04/18 DPP-IV Inhibitors PDL
10/04/18 Electrolyte Depleters PDL
04/04/19 Electrolyte Depleters – Potassium Lowering Agents PDL
05/16/07 Emsam®
12/03/18 Entresto Clinical Edit
01/31/19 Epinephrine Self-Injectable Agents PDL
01/19/06 Equetro®
08/01/17 Exondys 51® Clinical Edit
04/04/19 Fibromyalgia Agents PDL
10/04/18 Fluoroquinolones PDL
07/12/18 Fluoroquinolones – Ophthalmic PDL
07/12/18 Fluoroquinolones – Otic PDL
07/28/03 Forteo® (teriparatide injection / Parathyroid Hormone)
10/04/18 Gastrointestinal(GI) Antibiotics – Oral PDL
04/04/19 GI Motility Agents PDL
10/04/18 GLP-1 Receptor Agonists PDL
10/04/18 Growth Hormones and Growth Factors PDL
10/04/18 Hematopoietic Agents PDL
10/04/18 Hep C (HCV) Therapy
04/04/19 Hereditary Angioedema Treatment Agents PDL
07/12/18 Herpes Antivirals – Oral PDL
04/23/13 Human Papillomavirus Vaccines
03/01/19 Insulins Long Acting PDL
10/04/18 Insulins Mix PDL
10/04/18 Insulins PDL
10/04/18 Insulins Rapid Acting PDL
10/04/18 Intravaginal Antibiotics PDL
04/11/19 Jynarque Clinical Edit
11/13/03 Klonopin Wafer® (clonazepam)
07/12/18 Leukotriene Modifiers PDL
01/10/19 Lipotropic Agents: Homozygous FamilialHyperchloesterolemia PDL
01/10/19 Lipotropic Agents: Niacin Derivatives PDL
01/10/19 Lipotropic Agents: Proprotein Convertase SubtilisinKexin Type 9 (PCSK9) Binder PDL
01/10/19 Lipotropic Agents: Statins (HMG Co-A ReductaseInhibitors) and Combination Products PDL
01/10/19 Lipotropic Agents: Triglyceride Lowering Agents PDL
04/18/19 Luxturna Clinical Edit
10/04/18 Macrolides PDL
07/12/18 Mast Cell Stabilizers – Prostaglandin Agonists(Glaucoma Agents) PDL
04/18/19 Megestrol Acetate
10/04/18 Methotrexate Oral and Injectable PDL
04/04/19 Morphine Milligram Equivalent Accumulation
10/04/18 Multiple Sclerosis Agents PDL
02/01/19 Narcolepsy Inhibitors
04/04/19 Neuropathic Pain Agents PDL
09/07/05 Niravam Clinical Edit
04/04/19 Non-Ergot Dopamine Receptor Agonists PDL
02/15/17 Non-Oral Contraceptives Fiscal Edit
04/04/19 NSAID Agents PDL
07/12/18 NSAIDs – Ophthalmic PDL
05/03/07 Nubain®
05/23/13 Onfi (clobazam)
04/04/19 Opioid Dependence Agents PDL
04/04/19 Opioid Emergency Reversal Agents PDL
04/04/19 Opioid - Long Acting PDL
04/11/19 Opioids, Combination Short-Acting Clinical Edit
05/16/19 Opioids, Short Acting Clinical Edits
10/04/18 Oral AntiDiabetic: Alpha - Glucosidase Inhibitors PDL
10/04/18 Oral AntiDiabetic: Biguanides PDL
10/04/18 Oral AntiDiabetic: Meglintinides PDL
10/04/18 Oral AntiDiabetic: Sulfonylureas 2nd Generation PDL
10/04/18 Oral AntiDiabetic: Thiazolidinediones PDL
01/31/05 Oxandrin®
04/18/19 Palynziq Clinical Edit
07/12/18 Pancreatic Enzyme Agents PDL
10/04/18 Penicillins PDL
05/16/19 Polyneuropathy hATTR Clinical Edit
09/26/05 Prostin VR® Pediatric
07/12/18 Protaglandin Agonists (Glaucoma Agents) PDL
01/10/19 Proton Pump Inhibitors PDL
07/12/18 Psoriasis Agents - Oral PDL
07/12/18 Psoriasis Agents – Topical PDL
11/12/10 Psychotropic Medications Polypharmacy
01/10/19 Pulmonary Arterial Hypertension (PAH) Agents (Inhaled and Injectable) PDL
01/10/19 Pulmonary Arterial Hypertension (PAH) Agents (Oral) PDL
07/07/11 Ranexa®
08/02/17 Respiratory Monoclonal Antibodies Clinical Edit
07/12/18 Retinoids – Topical PDL
10/12/16 Ribavirins PDL
04/04/19 Sedative Hypnotics PDL
07/07/11 Selzentry® (Maraviroc)
04/04/19 Skeletal Muscle Relaxants PDL
05/02/19 SNRI Clinical Edit
10/04/18 Sodium - Glucose Co - Transporter 2 (SGLT2) PDL
08/01/17 Spinraza® Clinical Edit
05/02/19 SSRI Clinical Edit
01/10/19 Sympatholytic Agents PDL
09/16/10 Synagis (palivizumab)
10/04/18 Targeted Immune Modulators (Formerly Biologics - DMARDs) PDL
12/14/18 Tetracyclines PDL
04/04/19 ThromobocytopeniaTreatment Agents PDL
07/12/18 Topical Antiviral Agents
04/04/19 Tramadol-like Agents PDL
01/16/04 Tricyclic Antidepressant Coordination of Care
07/12/18 Ulcerative Colitis Oral Agents PDL
01/17/19 Ulcerative Colitis-Rectal PDL
10/04/18 Urinary Tract Antispasmodics PDL
03/07/03 Voriconazole (Vfend) / Antifungal
11/13/03 Xanax XR® (Alprazolam)
11/13/03 Zometa® (zoledronic acid)
07/03/12 Zostavax Injection