MO HealthNet is continuing the state specific Preferred Drug List and Clinical Edit processes. The following is a listing of therapeutic classes that have been implemented. Please see the implementation schedule for proposed implementation dates for additional classes.

Issue Date Pharmacy Clinical Edit and PDL Description
08/15/19 15 Day Limitation Fiscal Edit
11/06/18 15-Day Supply - Oral Oncology
07/18/19 5-HTI Serotonin Receptor Agonists (Triptans) PDL
01/10/19 ACE Inhibitors PDL
01/10/19 ACE Inhibitors/Calcium Channel Blocker Combinations PDL
01/10/19 Ace Inhibitors/Diuretic Combinations PDL
07/11/19 Actinic Keratosis Agents – Topical PDL
10/03/19 ADHD Therapy
04/04/19 Alzheimer’s Agents & Cholinesterase Inhibitors PDL 
07/07/11 Ampyra
10/03/19 Amylin Analogs PDL
07/11/19 Androgenic Agents – Topical PDL
01/10/19 Angiotensin Receptor Blocker Diuretic Combinations PDL
01/10/19 Angiotensin Receptor Blockers PDL
01/10/19 Angiotensin II Receptor-Calcium Channel Blocker Combinations PDL
07/11/19 Antibiotic Agents – Inhaled PDL
01/10/19 Anticoagulants Agents: Oral and Subcutaneous PDL
10/03/19 AntiDiabetic Combinations: Oral and Injectable PDL
10/17/19 Antiemetics –5-HT3 Agents & Other PDL
04/04/19 Antiemetics –THC Derivative Agents PDL
11/07/19 Antifungal Agents – Topical PDL
07/11/19 Antifungal (Onychomycosis – Candidiasis) Agents PDL
07/11/19 Antihistamine Decongestant Combos
07/11/19 Antihistamines – Intranasal PDL
07/11/19 Antihistamines - Low Sedating
07/11/19 Antihistamines - Ophthalmic
10/03/19 Antihyperuricemic Agents PDL
10/03/19 Antiparasitic Agents – Topical PDL
04/04/19 Anti-Parkinsonism MAOB Inhibitors PDL
01/10/19 Antiplatelet Agents
06/13/19 Antipsychotics– 2nd Generation (Atypicals) PDL
07/11/09 Antivirals - Topical PDL
08/08/19 Atopic Dermatitis Agents (Immunomodulators)
10/10/19 Benzodiazepines (Select Oral) Clinical Edit
07/11/19 Benzoyl Peroxide-Antibiotic Combination PDL
07/11/19 Beta Adrenergic Agents Long Acting PDL
07/11/19 Beta Adrenergic Agents/Nebulized PDL
07/11/19 Beta Adrenergic Beta Blockers - Short Acting PDL
01/10/19 Beta Adrenergic Blockers and Diuretic Combinations PDL
10/31/17 BiDil® Tablets Clinical Edit
10/03/19 Bile Salts Agents PDL
10/03/19 Bone Ossification Suppression Agents
10/24/19 Botulinum Toxin Clinical Edit
10/03/19 BPH Agents PDL (formerly Androgen Hormone Inhibitors)
10/17/19 Brand Over Generic
10/17/19 Butalbital Combo Clinical Edit
01/10/19 Calcium Channel Blockers (Dihydropyridines) PDL
01/10/19 Calcium Channel Blockers (Non-Dihydropyridines) PDL
06/21/18 CAR T Clinical Edit
10/03/19 Cephalosporin Antibiotics – Oral PDL
08/01/19 CGRP Inhibitors
10/24/19 Clobazam Agents Clinical Edit
10/03/19 Colony Stimulating Factors
07/11/19 COPD Anticholinergic Agents PDL
12/03/18 Corlanor Clinical Edit
07/11/19 Corticosteroids Oral – Inhaled PDL
07/11/19 Corticosteroids - Intranasal PDL
07/11/19 Corticosteroids - Ophthalmic PDL
07/11/19 Corticosteroids-Topical PDL
07/12/19 Cough and Cold PDL
04/04/19 COX-2 Inhibitors PDL
10/03/19 Cryopyrin-Associated Periodic Syndrome (CAPS) Agents PDL
04/11/19 Crysvita Clinical Edit
08/01/19 Diabetic Supply Quantity Limit Fiscal Edit
01/10/19 Direct Renin Inhibitors and Combinations PDL
11/13/03 Dolgic LQ® (Acetaminophen/Butalbital/Caffeine)
11/07/19 Dose Optimization Fiscal Edit
10/03/19 DPP-IV Inhibitors PDL
10/03/19 Electrolyte Depleters PDL
10/03/19 Electrolyte Depleters – Potassium Lowering Agents PDL
05/16/07 Emsam®
12/03/18 Entresto Clinical Edit
10/24/19 Epidiolex Clinical Edit
07/11/19 Epinephrine Self-Injectable Agents PDL
06/20/19 Equetro Clinical Edit®
10/03/19 Erythropoiesis Stimulating Agents PDL
08/01/17 Exondys 51® Clinical Edit
08/08/19 Fibromyalgia Agents PDL
10/03/19 Fluoroquinolones PDL
07/11/19 Fluoroquinolones – Ophthalmic PDL
07/11/19 Fluoroquinolones – Otic PDL
07/28/03 Forteo® (teriparatide injection / Parathyroid Hormone)
05/23/19 Galafold™ (migalastat) Clinical Edit
10/17/19 Gamifant Clinical Edit
10/03/19 Gastrointestinal(GI) Antibiotics – Oral PDL
04/04/19 GI Motility Agents PDL
10/24/19 Glaucoma Agents PDL
10/03/19 GLP-1 Receptor Agonists PDL
10/03/19 Growth Hormones and Growth Factors PDL
10/03/19 Hep C (HCV) Therapy
08/12/19 Hereditary Angioedema Treatment Agents PDL
07/11/19 Herpes Antivirals – Oral PDL
08/01/19 Hospice Fiscal Edit
10/03/19 Insulins Long Acting PDL
10/03/19 Insulins Mix PDL
10/03/19 Insulins-Non-Ananlog PDL
10/03/19 Insulins Rapid Acting PDL
04/11/19 Jynarque Clinical Edit
07/11/19 Leukotriene Modifiers PDL
01/10/19 Lipotropic Agents: Homozygous FamilialHyperchloesterolemia PDL
01/10/19 Lipotropic Agents: Niacin Derivatives PDL
01/10/19 Lipotropic Agents: Proprotein Convertase SubtilisinKexin Type 9 (PCSK9) Binder PDL
01/10/19 Lipotropic Agents: Statins (HMG Co-A ReductaseInhibitors) and Combination Products PDL
01/10/19 Lipotropic Agents: Triglyceride Lowering Agents PDL
04/18/19 Luxturna Clinical Edit
10/03/19 Macrolides PDL
07/11/19 Mast Cell Stabilizers - Ophthalmic PDL
04/18/19 Megestrol Acetate
10/03/19 Methotrexate Products
04/04/19 Morphine Milligram Equivalent Accumulation
10/03/19 Multiple Sclerosis Agents PDL
02/01/19 Narcolepsy Inhibitors
04/04/19 Neuropathic Pain Agents PDL
08/22/19 Nocturnal Polyuria Clinical Edit
04/04/19 Non-Ergot Dopamine Receptor Agonists PDL
09/19/19 Non-Oral Contraceptives Fiscal Edit
04/04/19 NSAID Agents PDL
07/11/19 NSAIDs – Ophthalmic PDL
05/03/07 Nubain®
10/10/19 Opioid Dependence Agents PDL
04/04/19 Opioid Emergency Reversal Agents PDL
10/03/19 Opioid - Long Acting PDL
04/11/19 Opioids, Combination Short-Acting Clinical Edit
05/16/19 Opioids, Short Acting Clinical Edits
10/03/19 Oral AntiDiabetic: Alpha - Glucosidase Inhibitors PDL
10/03/19 Oral AntiDiabetic: Biguanides PDL
10/03/19 Oral AntiDiabetic: Meglintinides PDL
10/03/19 Oral AntiDiabetic: Thiazolidinediones PDL
07/24/19 Orilissa Clinical Edit
01/31/05 Oxandrin®
10/17/19 Oxervate Clinical Edit
04/18/19 Palynziq Clinical Edit
07/11/19 Pancreatic Enzyme Agents PDL
10/03/19 Penicillins PDL
05/16/19 Polyneuropathy hATTR Clinical Edit
01/10/19 Proton Pump Inhibitors PDL
07/11/19 Psoriasis Agents - Oral PDL
07/11/19 Psoriasis Agents – Topical PDL
08/05/19 Psychotropic Medications Polypharmacy
08/22/19 Pulmonary Arterial Hypertension (PAH) Agents (Inhaled and Injectable) PDL
08/01/19 Pulmonary Arterial Hypertension (PAH) Agents (Oral) PDL
07/07/11 Ranexa®
10/17/19 Respiratory Monoclonal Antibodies PDL
07/11/19 Retinoids – Topical PDL
10/12/16 Ribavirins PDL
10/03/19 Second Generation Sulfonylureas PDL
08/08/19 Sedative Hypnotics PDL
06/20/19 Selzentry® (Maraviroc)
04/04/19 Skeletal Muscle Relaxants PDL
05/02/19 SNRI Clinical Edit
10/03/19 Sodium - Glucose Co - Transporter 2 (SGLT2) PDL
08/01/17 Spinraza® Clinical Edit
09/26/19 SSRI Clinical Edit
08/29/19 Sympatholytic Agents PDL
10/10/19 Synagis Clinical Edit
08/22/19 Systemic Antifungals Clinical Edit
10/03/19 Targeted Immune Modulators (Formerly Biologics - DMARDs) PDL
10/03/19 Tetracyclines PDL
10/03/19 ThromobocytopeniaTreatment Agents PDL
04/04/19 Tramadol - like Agents PDL
08/29/19 Ulcerative Colitis Oral Agents PDL
07/11/19 Ulcerative Colitis - Rectal PDL
10/03/19 Urinary Tract Antispasmodics PDL
10/03/19 Vaginal Antibiotics PDL
03/07/03 Voriconazole (Vfend) / Antifungal
11/13/03 Zometa® (zoledronic acid)